Description

2-β-D-Ribofuranosyl-4-Thiazolecarboxylic Acid Ethyl Ester CAS NO 95936-53-1 is a high-purity nucleoside derivative and a key synthetic intermediate in the production of modified nucleotides and antiviral agents. This compound is critical for pharmaceutical research and development, particularly in the synthesis of novel therapeutic candidates targeting viral replication. It is primarily utilized by research institutions, pharmaceutical manufacturers, and fine chemical suppliers engaged in the development of nucleoside analogs and antiviral drugs.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel nucleoside-based antiviral and anticancer agents.
• Biochemical Research: Used in the study of enzyme mechanisms, nucleic acid chemistry, and the development of molecular probes.
• Antiviral Drug Development: Serves as a precursor in the research and production of compounds designed to inhibit viral polymerases.
• Nucleoside Chemistry: Employed in the synthesis of modified ribonucleosides and thiazole-containing nucleotide analogs for structure-activity relationship (SAR) studies.
• Fine Chemical Synthesis: Used as a specialized intermediate in custom synthesis and contract manufacturing for advanced chemical entities.

Basic Information

Product Name	2-β-D-Ribofuranosyl-4-Thiazolecarboxylic Acid Ethyl Ester
CAS No.	95936-53-1
Molecular Formula	C11H15NO6S
Molecular Weight	289.31 g/mol
Synonyms	4-Thiazolecarboxylic acid, 2-β-D-ribofuranosyl-, ethyl ester; Ethyl 2-β-D-ribofuranosyl-1,3-thiazole-4-carboxylate; 2-β-D-Ribofuranosylthiazole-4-carboxylic acid ethyl ester; Tiazofurin intermediate; Ribosylthiazolecarboxylate ethyl ester; NSC 286193; 2-(β-D-Ribofuranosyl)-4-thiazolecarboxylic Acid Ethyl Ester
EINECS	Contact for details

Quality Control

Our 2-β-D-Ribofuranosyl-4-Thiazolecarboxylic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) with detailed batch-specific data are provided to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.