Description

1-Amino-6-(2-Nitrobenzenesulfonamido)Hexane Hydrochloride is a specialized organic intermediate featuring a primary amine group protected by a 2-nitrobenzenesulfonyl (o-Nosyl) group. This compound is valued for its role as a key building block in sophisticated organic synthesis, particularly in peptide chemistry and pharmaceutical research where selective amine protection and deprotection strategies are critical. It is primarily sought after by research institutions, fine chemical manufacturers, and pharmaceutical development companies engaged in creating novel active pharmaceutical ingredients (APIs) and complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the multi-step synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Peptide Synthesis: Used as a protected amino acid derivative or linker in solid-phase and solution-phase peptide synthesis, leveraging the ortho-nitrobenzenesulfonamide (o-Nosyl) protecting group for the amine functionality.
• Chemical Research & Development: Employed in academic and industrial R&D labs for exploring new synthetic methodologies and creating novel chemical entities.
• Bioconjugation Chemistry: Acts as a reagent for introducing amine-reactive handles or spacers in the modification of biomolecules like proteins and antibodies.
• Fine Chemical Production: Utilized in the manufacture of high-value specialty chemicals, agrochemicals, and advanced materials requiring specific amine-protected intermediates.

Basic Information

Product Name	1-Amino-6-(2-Nitrobenzenesulfonamido)Hexane Hydrochloride
CAS No.	95915-82-5
Molecular Formula	C₁₂H₂₀N₄O₄S • HCl
Molecular Weight	360.84 g/mol
Synonyms	N-(6-Aminohexyl)-2-nitrobenzenesulfonamide hydrochloride; 6-[(2-Nitrobenzenesulfonyl)amino]hexan-1-amine hydrochloride; 1-Hexanamine, 6-[(2-nitrophenyl)sulfonyl]amino]-, hydrochloride; o-Nosyl protected hexamethylenediamine hydrochloride; Nosyl-C6-NH2•HCl; 2-Nitro-N-(6-aminohexyl)benzenesulfonamide hydrochloride
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for research and fine chemical use. Each batch is characterized to confirm identity, purity, and consistency. Certificates of Analysis (COA) detailing specific test results are available upon request. We support development projects requiring high-purity intermediates with reliable and traceable quality documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.