Description

n-[2-[(2,3-Dihydro-1,5-Dimethyl-3-Oxo-2-Phenyl-1H-Pyrazol-4-Yl)Amino]-2-Oxoethyl]Nicotinamide Monohydrochloride is a high-purity pharmaceutical intermediate and research chemical. This compound is valued for its role as a key building block in the synthesis of more complex active pharmaceutical ingredients (APIs) and for its utility in biochemical research. It is primarily sought by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions engaged in medicinal chemistry and drug discovery programs.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of target drug molecules, particularly in therapeutic areas requiring pyrazole and nicotinamide derivatives.
• Medicinal Chemistry Research: Used as a scaffold or building block for designing and synthesizing novel chemical entities for biological screening and structure-activity relationship (SAR) studies.
• Biochemical Reagent: Employed in research to study enzyme interactions, receptor binding, or as a standard in analytical method development.
• Fine Chemical Synthesis: Serves as a specialized raw material for the production of high-value, low-volume chemicals used in advanced applications.
• Reference Standard: Utilized as a certified reference material (CRM) for quality control and analytical testing in pharmaceutical manufacturing.

Basic Information

Product Name	n-[2-[(2,3-Dihydro-1,5-Dimethyl-3-Oxo-2-Phenyl-1H-Pyrazol-4-Yl)Amino]-2-Oxoethyl]Nicotinamide Monohydrochloride
CAS No.	95873-63-5
Molecular Formula	C19H20ClN5O3
Molecular Weight	401.85 g/mol
Synonyms	N-[2-[[(1,5-Dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)amino]oxoacetyl]]nicotinamide hydrochloride; 4-[[(2-Carbamoylpyridin-3-yl)formamido]acetyl]amino]-1,5-dimethyl-2-phenylpyrazol-3-one hydrochloride; Nicotinamide, N-[2-[[(1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)amino]oxoacetyl]]-, hydrochloride; 95873-63-5; Antipyrine nicotinamide derivative hydrochloride
EINECS	Contact for details

Quality Control

Our n-[2-[(2,3-Dihydro-1,5-Dimethyl-3-Oxo-2-Phenyl-1H-Pyrazol-4-Yl)Amino]-2-Oxoethyl]Nicotinamide Monohydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets exacting standards for research and synthesis. Certificates of Analysis (COA) detailing batch-specific results are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.