Description

n-[(2α,4α,5β)-4-[[2-(Acetylamino)-2-Deoxy-4-o-Sodiosulfo-β-D-Glucopyranosyl]Oxy]-5-(Hydroxymethyl)-L-Prolyl]-β-Alanine is a sophisticated, high-purity synthetic intermediate of significant importance in advanced pharmaceutical research and development. This compound matters because it serves as a critical building block for the synthesis of complex glycopeptide-based therapeutics, offering researchers precise control over molecular structure. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and biotechnology industries working on novel drug candidates, particularly in areas like targeted therapies and specialized antibiotics.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel glycopeptide antibiotics and other complex therapeutic agents.
• Bioconjugation Research: Used in the development of antibody-drug conjugates (ADCs) and other targeted drug delivery systems due to its functionalized structure.
• Carbohydrate Chemistry: Serves as a valuable substrate for studying enzymatic glycosylation and developing new synthetic methodologies for complex sugars.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to optimize the pharmacokinetic and pharmacodynamic properties of lead compounds.
• Process Chemistry: Used in scale-up and optimization of synthetic routes for active pharmaceutical ingredients (APIs) requiring this specific molecular scaffold.

Basic Information

Product Name	n-[(2α,4α,5β)-4-[[2-(Acetylamino)-2-Deoxy-4-o-Sodiosulfo-β-D-Glucopyranosyl]Oxy]-5-(Hydroxymethyl)-L-Prolyl]-β-Alanine
CAS No.	95863-92-6
Molecular Formula	C₂₁H₃₄N₄O₁₃S•Na
Molecular Weight	605.57 g/mol
Synonyms	β-Alanine, N-[(2α,4α,5β)-4-[[2-(acetylamino)-2-deoxy-4-O-sodiosulfo-β-D-glucopyranosyl]oxy]-5-(hydroxymethyl)-1-pyrrolidinyl]carbonyl]-; N-[(2α,4α,5β)-4-({2-[(Acetyl)amino]-2-deoxy-4-O-sulfo-β-D-glucopyranosyl}oxy)-5-(hydroxymethyl)-L-prolyl]-β-alanine sodium salt; Glycopeptide intermediate 95863-92-6; Sodium (2S,4S,5R)-5-(hydroxymethyl)-1-{3-[(2S)-2-({2-[(2R,3R,4R,5S,6R)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-3-hydroxypropanoyl)amino]propanoyl}pyrrolidine-2-carboxylate 4-sulfate
EINECS	Contact for details

Quality Control

Our n-[(2α,4α,5β)-4-[[2-(Acetylamino)-2-Deoxy-4-o-Sodiosulfo-β-D-Glucopyranosyl]Oxy]-5-(Hydroxymethyl)-L-Prolyl]-β-Alanine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.