Description

(2S)-2-(Adamantan-1-Yl)-2-Aminoacetic Acid CAS NO 95853-35-3 is a high-purity, chiral amino acid derivative featuring the rigid adamantane scaffold. This compound is a critical chiral building block and intermediate in advanced pharmaceutical synthesis, offering unique steric and lipophilic properties. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and fine chemical industries for the development of novel active pharmaceutical ingredients (APIs), particularly in areas like antiviral and neurological therapeutics.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and production of novel drug candidates, especially protease inhibitors and other targeted therapies.
• Peptidomimetics Development: Used to incorporate the adamantyl group into peptide backbones, enhancing metabolic stability and membrane permeability of potential drug molecules.
• Asymmetric Synthesis: Serves as a valuable starting material or auxiliary in catalytic asymmetric reactions to create enantiomerically pure compounds.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies to explore the impact of the bulky, lipophilic adamantane moiety on biological activity.
• Fine Chemical Synthesis: Acts as a specialized building block for the synthesis of complex organic molecules with potential agrochemical or material science applications.
• Reference Standard: Supplied as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	(2S)-2-(Adamantan-1-Yl)-2-Aminoacetic Acid
CAS No.	95853-35-3
Molecular Formula	C₁₂H₁₉NO₂
Molecular Weight	209.29 g/mol
Synonyms	(S)-2-Adamantylglycine; (S)-2-Amino-2-(adamantan-1-yl)acetic acid; L-Adamantylglycine; (2S)-2-Amino-2-(tricyclo[3.3.1.1³,⁷]dec-1-yl)acetic acid; 1-Adamantyl-L-glycine; NSC 339587; (S)-α-Aminoadamantaneacetic acid
EINECS	Contact for details

Quality Control

Our (2S)-2-(Adamantan-1-Yl)-2-Aminoacetic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and production. A detailed Certificate of Analysis (COA) providing batch-specific results for identity, purity, and impurities is supplied with every order.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere or in a desiccator after opening to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.