Description

(R)-Benzyl 4-Oxoazetidine-2-Carboxylate CAS NO 95729-87-6 is a high-purity chiral building block belonging to the azetidine class of strained heterocycles. This compound is of significant value in pharmaceutical research and development, serving as a key intermediate for the synthesis of novel active pharmaceutical ingredients (APIs) and complex molecules. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing β-lactam analogs and other nitrogen-containing scaffolds.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of β-lactam antibiotics, protease inhibitors, and other bioactive molecules.
• Asymmetric Synthesis: Used as a starting material or chiral template in stereoselective reactions to introduce the azetidinone ring system.
• Medicinal Chemistry Research: Employed in lead optimization and structure-activity relationship (SAR) studies to explore new chemical entities.
• Process Chemistry: Serves as a key intermediate in the scale-up and commercial route development for target drug candidates.
• Agrochemical Development: Potential use in creating novel herbicides or fungicides with unique modes of action.
• Academic Research: Utilized in methodological studies exploring ring strain, cycloaddition reactions, and heterocyclic chemistry.

Basic Information

Product Name	(R)-Benzyl 4-Oxoazetidine-2-Carboxylate
CAS No.	95729-87-6
Molecular Formula	C11H11NO3
Molecular Weight	205.21 g/mol
Synonyms	(R)-Benzyl 2-carboxy-4-azetidinone; (R)-Benzyl 2-carboxyazetidin-4-one; (2R)-4-Oxo-2-azetidinecarboxylic Acid Benzyl Ester; (R)-Benzyl 4-Oxo-2-azetidinecarboxylate; (R)-Benzyl Azetidine-2-carboxylate-4-one; (R)-Benzyl β-Lactam-2-carboxylate; (R)-Benzyl 4-Azetidinone-2-carboxylate; (R)-Benzyl N-Carboxyazetidin-4-one
EINECS	Contact for details

Quality Control

Our (R)-Benzyl 4-Oxoazetidine-2-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure compliance with exacting standards for research and development use. Certificates of Analysis (COA) detailing identity, purity, and chiral excess are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound may be moisture-sensitive; keep the container tightly sealed in a dry environment. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.