Description

2-Bromo-1-[4-(Trifluoromethyl)Phenyl]Propan-1-One, 4-(2-Bromopropanoyl)Benzotrifluoride is a high-value organic building block characterized by its bromoacetyl and trifluoromethylphenyl functional groups. This compound matters for its role as a critical intermediate in the synthesis of complex molecules, particularly in advanced pharmaceutical and agrochemical research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those requiring a trifluoromethylphenyl moiety for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides where the trifluoromethyl group improves lipophilicity and biological activity.
• Material Science Research: Serves as a building block for creating specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and inhibitors for studying enzyme mechanisms and biological pathways.
• Cross-Coupling Reactions: Acts as an electrophilic partner in various palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) to form complex biaryl structures.
• Fluorine Chemistry: A valuable substrate for further functionalization in fluorine chemistry, exploring the unique properties imparted by the CF3 group.

Basic Information

Product Name	2-Bromo-1-[4-(Trifluoromethyl)Phenyl]Propan-1-One, 4-(2-Bromopropanoyl)Benzotrifluoride
CAS No.	95728-57-7
Molecular Formula	C10H8BrF3O
Molecular Weight	281.07 g/mol
Synonyms	2-Bromo-1-(4-(trifluoromethyl)phenyl)propan-1-one; 4'-(Trifluoromethyl)-2-bromopropiophenone; 1-(4-Trifluoromethylphenyl)-2-bromopropan-1-one; 2-Bromo-4'-trifluoromethylpropiophenone; 4-(2-Bromopropionyl)benzotrifluoride; α-Bromopropiophenone, 4'-trifluoromethyl-; p-Trifluoromethyl-α-bromopropiophenone; Benzotrifluoride, 4-(2-bromopropanoyl)-
EINECS	Contact for details

Quality Control

Our 2-Bromo-1-[4-(Trifluoromethyl)Phenyl]Propan-1-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture. Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.