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(7A,17A)-17-Hydroxy-3-Oxo-Pregna-4,9(11)-Diene-7,21-Dicarboxylicacid G-Lactone Methyl Ester CAS NO 95716-70-4


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CAS No.:95716-70-4

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

(7A,17A)-17-Hydroxy-3-Oxo-Pregna-4,9(11)-Diene-7,21-Dicarboxylicacid G-Lactone Methyl Ester is a high-purity steroid derivative and a key synthetic intermediate in advanced pharmaceutical research and development. This compound is valued for its specific structural framework, which is crucial for the synthesis of novel therapeutic agents, particularly in the fields of endocrinology and anti-inflammatory drug discovery. It is primarily utilized by research institutions, pharmaceutical development laboratories, and fine chemical manufacturers requiring precise and reliable building blocks for complex organic synthesis.

Application

  • Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of specialized steroid-based active pharmaceutical ingredients (APIs).
  • Research & Development: Used in medicinal chemistry for the design, synthesis, and biological evaluation of new chemical entities targeting hormone receptors.
  • Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
  • Process Chemistry: Employed in scale-up and optimization studies for the commercial production of steroid drugs.
  • Biochemical Research: Used as a tool compound to study steroid metabolism and enzyme interactions in vitro.

Basic Information

Item Detail
Product Name (7A,17A)-17-Hydroxy-3-Oxo-Pregna-4,9(11)-Diene-7,21-Dicarboxylicacid G-Lactone Methyl Ester
CAS No. 95716-70-4
Molecular Formula C25H30O6
Molecular Weight 426.51 g/mol
Synonyms 17-Hydroxy-3-oxopregna-4,9(11)-diene-7,21-dicarboxylic acid, 7,21-lactone, methyl ester; (7α,17α)-17-Hydroxy-3-oxopregna-4,9(11)-diene-7,21-dicarboxylic acid γ-lactone methyl ester; 7α,17α-Dihydroxy-3-oxo-17a-pregna-4,9(11)-diene-21-carboxylic acid γ-lactone methyl ester; Canrenone methyl ester derivative; Steroid lactone intermediate
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Quality Control

Our (7A,17A)-17-Hydroxy-3-Oxo-Pregna-4,9(11)-Diene-7,21-Dicarboxylicacid G-Lactone Methyl Ester is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR and NMR for structural confirmation, and residual solvent analysis, to ensure it meets the exacting standards required for pharmaceutical R&D. A Certificate of Analysis (COA) documenting all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Identification (HPLC) Retention time matches reference standard
Purity (HPLC) ≥ 98.0%
Related Substances (HPLC) Total impurities ≤ 2.0%
Single Maximum Impurity ≤ 0.5%
Loss on Drying ≤ 0.5%
Residue on Ignition ≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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