Description

4-Biphenylhydracrylic Acid, 4'-Fluoro-β-(m-Tolyl)-, (-)- is a specialized chiral organic compound belonging to the biphenylhydracrylic acid derivative family, identified by CAS No. 95711-58-3. This high-purity intermediate is valued for its unique stereochemistry and functional groups, which make it a critical building block in advanced synthetic chemistry. It is primarily sought after by research institutions and pharmaceutical development companies engaged in the synthesis of novel active pharmaceutical ingredients (APIs) and complex organic molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new therapeutic agents, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Asymmetric Synthesis: Used as a precursor or ligand in catalytic asymmetric reactions to induce chirality in target molecules.
• Chemical Research: Serves as a model compound in methodological studies for constructing complex biphenyl and fluorinated aromatic systems.
• Material Science Precursor: Potential use in the development of advanced organic materials, such as liquid crystals or specialty polymers, due to its rigid biphenyl core and fluorinated moiety.
• Reference Standard: Employed as a high-purity analytical standard for quality control and method validation in pharmaceutical analysis.

Basic Information

Product Name	4-Biphenylhydracrylic Acid, 4'-Fluoro-β-(m-Tolyl)-, (-)-
CAS No.	95711-58-3
Molecular Formula	C21H17FO2
Molecular Weight	320.36 g/mol
Synonyms	(-)-4'-Fluoro-β-(m-tolyl)-4-biphenylhydracrylic acid; (2S)-3-(4'-Fluoro[1,1'-biphenyl]-4-yl)-3-(3-methylphenyl)propanoic acid; 4'-Fluoro-β-(3-methylphenyl)-[1,1'-biphenyl]-4-propanoic acid, (S)-; 95711-58-3; 4-Biphenylpropanoic acid, 4'-fluoro-β-(3-methylphenyl)-, (βS)-; (S)-4'-Fluoro-β-(m-tolyl)-4-biphenylhydracrylic acid; [1,1'-Biphenyl]-4-propanoic acid, 4'-fluoro-β-(3-methylphenyl)-, (βS)-
EINECS	Contact for details

Quality Control

Our 4-Biphenylhydracrylic Acid, 4'-Fluoro-β-(m-Tolyl)-, (-)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis, to ensure it meets the high standards required for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound is light-sensitive and should be handled and stored away from strong acids and organic solvents to maintain stability. Keep the container tightly sealed when not in use to prevent contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.