Description

Diendo-3-Amino-Bicyclo[2.2.1]Heptane-2-Carboxylic Acid Ethyl Ester Hydrochloride is a high-purity, pharmaceutically relevant chiral building block. This compound is valued for its rigid, bicyclic structure which serves as a key scaffold in medicinal chemistry for the synthesis of novel drug candidates. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of central nervous system (CNS) agents, enzyme inhibitors, and other bioactive molecules requiring constrained amino acid analogs.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the research and development of new active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a constrained, bicyclic analog of amino acids to explore structure-activity relationships (SAR) and improve metabolic stability.
• Peptidomimetics: Incorporated into peptide backbones to create rigid, protease-resistant analogs for therapeutic applications.
• Asymmetric Synthesis: Serves as a starting material or auxiliary in the synthesis of enantiomerically pure compounds.
• Ligand Development: Potential use in creating novel ligands for biological targets and catalysts.
• Academic & Industrial R&D: Fundamental research tool in organic synthesis and chemical biology.

Basic Information

Product Name	Diendo-3-Amino-Bicyclo[2.2.1]Heptane-2-Carboxylic Acid Ethyl Ester Hydrochloride
CAS No.	95630-76-5
Molecular Formula	C10H18ClNO2
Molecular Weight	219.71 g/mol
Synonyms	(1R,2S,3R,4S)-3-Aminobicyclo[2.2.1]heptane-2-carboxylic acid ethyl ester hydrochloride; endo-3-Amino-2-carbethoxybicyclo[2.2.1]heptane hydrochloride; Ethyl 3-endo-aminobicyclo[2.2.1]heptane-2-endo-carboxylate hydrochloride; Bicyclo[2.2.1]heptane-2-carboxylic acid, 3-amino-, ethyl ester, hydrochloride, (1R,2S,3R,4S)-; 3-Amino-2-ethoxycarbonylbicyclo[2.2.1]heptane hydrochloride
EINECS	Contact for details

Quality Control

Our Diendo-3-Amino-Bicyclo[2.2.1]Heptane-2-Carboxylic Acid Ethyl Ester Hydrochloride is manufactured under controlled conditions to ensure high chemical purity and batch-to-batch consistency. Quality is verified through a comprehensive suite of analytical techniques including HPLC, NMR, and chiral analysis. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each batch to support your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.