Description

Ethyl 3-Endo-Aminobicyclo[2.2.1]Hept-5-Ene-2-Endo-Carboxylate Hydrochloride is a high-purity, pharmaceutically relevant bicyclic amine building block. This compound is valued for its rigid, three-dimensional scaffold, which is crucial for imparting specific conformational properties in advanced drug molecules. It is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of central nervous system (CNS) active drugs and other therapeutic agents.
• Agrochemical Synthesis: Used as a precursor for creating novel pesticides and herbicides with specific stereochemical requirements.
• Asymmetric Catalysis: Serves as a chiral ligand precursor or auxiliary in stereoselective synthesis.
• Academic & Institutional Research: Employed in methodological studies and the discovery of new chemical entities in university and contract research organization (CRO) settings.
• Peptidomimetics Development: Its constrained structure makes it suitable for designing peptide mimics in drug discovery programs.

Basic Information

Product Name	Ethyl 3-Endo-Aminobicyclo[2.2.1]Hept-5-Ene-2-Endo-Carboxylate Hydrochloride
CAS No.	95630-74-3
Molecular Formula	C11H18ClNO2
Molecular Weight	231.72 g/mol
Synonyms	Ethyl 3-endo-Aminobicyclo[2.2.1]hept-5-ene-2-endo-carboxylate Hydrochloride; 5-Norbornene-2-endo-carboxylic acid, 3-endo-amino-, ethyl ester, hydrochloride; Ethyl 3-Amino-5-norbornene-2-carboxylate Hydrochloride (endo,endo isomer); Bicyclo[2.2.1]hept-5-ene-2-endo-carboxylic acid, 3-endo-amino-, ethyl ester, hydrochloride; 2-Carbethoxy-3-endo-aminonorborn-5-ene Hydrochloride; 3-endo-Amino-5-norbornene-2-endo-ethylcarboxylate HCl; 95630-74-3
EINECS	Contact for details

Quality Control

Our Ethyl 3-Endo-Aminobicyclo[2.2.1]Hept-5-Ene-2-Endo-Carboxylate Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral integrity, to ensure compliance with exacting research and pharmaceutical intermediate standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure containers are sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.