Description

Chloroacetyl-n-Hydroxyleucyl-Alanyl-Glycinamide is a specialized synthetic peptide derivative used in advanced biochemical research and pharmaceutical development. This compound serves as a critical building block or intermediate in the synthesis of more complex peptides and peptidomimetics, offering precise control over molecular structure. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors for drug discovery, proteomics studies, and the development of therapeutic agents.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel peptide-based drugs and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies and proteomics research to understand biological pathways.
• Peptide Synthesis: Serves as a protected or activated fragment in solid-phase and solution-phase peptide synthesis (SPPS).
• Drug Discovery: Employed in high-throughput screening (HTS) and structure-activity relationship (SAR) studies for identifying new therapeutic candidates.
• Protease Inhibitor Development: Acts as a precursor or core structure for designing specific protease inhibitors.
• Bioconjugation: The chloroacetyl group provides a handle for site-specific conjugation to antibodies, proteins, or other biomolecules.

Basic Information

Product Name	Chloroacetyl-n-Hydroxyleucyl-Alanyl-Glycinamide
CAS No.	95602-96-3
Molecular Formula	C15H26ClN5O6
Molecular Weight	407.85 g/mol
Synonyms	Chloroacetyl-Hydroxyleucyl-Alanyl-Glycinamide; N-Chloroacetyl-N-hydroxy-L-leucyl-L-alanylglycinamide; (2S)-2-[(2S)-2-[(2S)-2-(Chloroacetamido)-4-hydroxy-4-methylpentanamido]propanamido]acetamide; Chloroacetyl-Hleu-Ala-Gly-NH2; H-Hleu(ChloroAc)-Ala-Gly-NH2; Peptide Synthesis Intermediate 95602-96-3
EINECS	Contact for details

Quality Control

Our Chloroacetyl-n-Hydroxyleucyl-Alanyl-Glycinamide is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, MS for identity confirmation, and chiral analysis to ensure stereochemical integrity. Certificates of Analysis (COA) detailing purity, impurities, and physical characteristics are provided with every shipment to guarantee consistent quality and traceability for your research and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as indicated on the label or COA. Due to its hygroscopic nature, the container should be kept sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95.0%
Assay	≥ 97.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.