Description

4-Vinylsulfonylbenzoic Acid is a specialized bifunctional organic compound that serves as a high-value reactive intermediate. Its molecular structure, featuring both a vinyl sulfone group and a carboxylic acid moiety, makes it a versatile building block for creating covalent linkages in advanced materials. This product is essential for researchers and manufacturers in the pharmaceutical and specialty polymer sectors who require precise, stable cross-linking agents. We supply this material with a focus on consistent purity and reliable global availability.

Application

• Pharmaceutical Intermediate: Used in the synthesis of targeted covalent inhibitors (TCIs) and other bioactive molecules where the vinyl sulfone acts as a Michael acceptor.
• Bioconjugation Reagent: Serves as a linker for attaching small molecules, dyes, or drugs to proteins, antibodies, or peptides under mild conditions.
• Polymer Cross-Linking Agent: Imparts permanent, stable cross-links in specialty polymers and hydrogels, enhancing mechanical strength and chemical resistance.
• Surface Modification: Functionalizes materials like silica, gold nanoparticles, or polymers to introduce carboxylic acid groups for further coupling reactions.
• Material Science Research: A key precursor in developing novel organic frameworks, smart materials, and self-healing polymers.
• Analytical Chemistry: Can be used to develop affinity chromatography resins or sensors by immobilizing specific ligands.

Basic Information

Product Name	4-Vinylsulfonylbenzoic Acid
CAS No.	95535-40-3
Molecular Formula	C9H8O4S
Molecular Weight	212.22 g/mol
Synonyms	4-Ethenylsulfonylbenzoic Acid; Benzoic acid, 4-(ethenylsulfonyl)-; 4-(Vinylsulfonyl)benzoic Acid; p-Vinylsulfonylbenzoic Acid; VSB Acid; 4-Carboxyphenyl vinyl sulfone; p-Carboxyphenyl vinyl sulfone
EINECS	Contact for details

Quality Control

Our 4-Vinylsulfonylbenzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by FT-IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials such as strong bases and reducing agents. The container must be kept tightly sealed to protect this light-sensitive compound from degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.