Description

(6R,7R)-7α-Amino-8-Oxo-3-(1,2,3-Thiadiazol-5-Ylthiomethyl)-5-Thia-1-Azabicyclo[4.2.0]Oct-2-Ene-2-Carboxylic Acid is a key advanced pharmaceutical intermediate, specifically a cephalosporin nucleus derivative. This compound is critical for the synthesis of modern, broad-spectrum cephalosporin antibiotics, offering a foundation for developing drugs with enhanced efficacy. It is primarily required by pharmaceutical R&D laboratories and API manufacturers focused on next-generation anti-infective therapies.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of advanced third and fourth-generation cephalosporin antibiotics.
• Active Pharmaceutical Ingredient (API) Development: Used in research and process development for novel antibacterial agents targeting resistant pathogens.
• Chemical Synthesis Research: Employed in academic and industrial laboratories for studying structure-activity relationships in β-lactam chemistry.
• Process Chemistry: Integral in scaling up and optimizing manufacturing routes for final antibiotic drug substances.

Basic Information

Product Name	(6R,7R)-7α-Amino-8-Oxo-3-(1,2,3-Thiadiazol-5-Ylthiomethyl)-5-Thia-1-Azabicyclo[4.2.0]Oct-2-Ene-2-Carboxylic Acid
CAS No.	95529-25-2
Molecular Formula	C11H11N5O3S3
Molecular Weight	373.43 g/mol
Synonyms	7-ACA Thiadiazole Derivative; 7-Aminocephalosporanic Acid Thiadiazolylthiomethyl Derivative; 7β-Amino-3-[(1,2,3-thiadiazol-5-ylthio)methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid; Cephalosporin C Nucleus Analog; (6R,7R)-7-Amino-3-((1,2,3-thiadiazol-5-ylthio)methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our production of this high-value intermediate adheres to strict quality management systems, ensuring batch-to-batch consistency for critical pharmaceutical synthesis. Quality is verified through comprehensive analytical methods including HPLC, NMR, and MS. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed in a dry environment. For long-term storage, consider conditions under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.