Description

(3S,4R)-Methyl (3,4-Isopropylidenediooxypyrrolidin-2-ylidene) Acetate is a high-value chiral building block and synthetic intermediate characterized by its fused bicyclic structure. This compound matters for its role in facilitating the stereoselective synthesis of complex molecules, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, particularly in classes like protease inhibitors and other biologically active nitrogen-containing heterocycles.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides where specific stereochemistry is crucial for activity.
• Asymmetric Catalysis Ligand Precursor: Serves as a starting material for the development of novel chiral ligands and organocatalysts.
• Fine Chemical Production: Employed in the multistep synthesis of complex, high-value specialty chemicals and flavors & fragrances.
• Academic & Institutional Research: A valuable tool in organic chemistry laboratories for methodology development and studying stereochemical outcomes.
• Material Science: Potential intermediate for the synthesis of specialized polymers or functionalized surfaces requiring precise molecular architecture.

Basic Information

Product Name	(3S,4R)-Methyl (3,4-Isopropylidenediooxypyrrolidin-2-ylidene) Acetate
CAS No.	95456-60-3
Molecular Formula	C10H13NO5
Molecular Weight	227.21 g/mol
Synonyms	Methyl (3S,4R)-3,4-Isopropylidenedioxy-1-azabicyclo[3.1.0]hex-2-ene-2-carboxylate; (3S,4R)-3,4-O-Isopropylidene-3,4-dihydroxy-2-methoxycarbonyl-2H-pyrrole; 2H-Pyrrole-2-carboxylic acid, 3,4-dihydro-3,4-dihydroxy-, 3,4-O-(1-methylethylidene)-, methyl ester, (3S-cis)-; Methyl (3S-cis)-3,4-O-(1-methylethylidene)-3,4-dihydroxy-2H-pyrrole-2-carboxylate; Bicyclic Pyrrolidine Ester Intermediate
EINECS	Contact for details

Quality Control

Our (3S,4R)-Methyl (3,4-Isopropylidenediooxypyrrolidin-2-ylidene) Acetate is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high chemical purity, correct stereochemistry, and consistent performance. Specifications typically cover identity, assay (HPLC), enantiomeric excess (Chiral HPLC), and impurity profiles. Certificates of Analysis (COA) detailing all test results are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.