Description

2-Chloro-1,3-thiazole-5-carbaldehyde is a versatile heterocyclic building block characterized by its reactive aldehyde and chloro-substituted thiazole core. This compound is essential for the synthesis of complex molecules, particularly in the pharmaceutical and agrochemical sectors, where it serves as a key intermediate. It is primarily sought after by research chemists and process development teams working on active pharmaceutical ingredients (APIs), crop protection agents, and advanced material science applications.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly for antiviral, antibacterial, and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, leveraging its reactive sites for structural diversification.
• Material Science Research: Serves as a building block for creating functionalized polymers, ligands for catalysis, and organic electronic materials.
• Chemical Research & Development: Employed in academic and industrial R&D for exploring new heterocyclic chemistry and reaction pathways.
• Fine Chemical Production: Acts as a specialized intermediate in the multi-step synthesis of complex fine chemicals and dyes.

Basic Information

Product Name	2-Chloro-1,3-thiazole-5-carbaldehyde
CAS No.	95453-58-0
Molecular Formula	C4H2ClNOS
Molecular Weight	147.58 g/mol
Synonyms	2-Chloro-1,3-thiazole-5-carboxaldehyde; 2-Chlorothiazole-5-carbaldehyde; 5-Formyl-2-chlorothiazole; 2-Chloro-5-formylthiazole; 2-Chlorothiazole-5-carboxaldehyde; 95453-58-0; 2-Chloro-thiazole-5-carbaldehyde
EINECS	Contact for details

Quality Control

Our 2-Chloro-1,3-thiazole-5-carbaldehyde is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP standards for pharmaceutical applications and can tailor quality protocols to meet specific customer requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is easily oxidized and should be handled and stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.