Description

3'-Deamino-3'-Hydroxydaunorubicin is a chemically modified anthracycline derivative, primarily recognized as a key intermediate in the synthesis of advanced pharmaceutical compounds. This compound is valued for its role in developing novel therapeutic agents, particularly in oncology research. It is essential for pharmaceutical R&D laboratories, academic research institutions, and manufacturers focused on producing high-purity active pharmaceutical ingredients (APIs) and novel drug candidates.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel anthracycline-based chemotherapeutic agents and other specialized APIs.
• Oncology Research: Used in biochemical and pharmacological studies to investigate structure-activity relationships (SAR) and develop new anti-cancer therapies.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis (HPLC, LC-MS).
• Academic & Institutional R&D: Employed in university and research institute laboratories for studying drug metabolism, mechanism of action, and biochemical pathways.
• Process Development: Utilized in scaling up and optimizing synthetic routes for the commercial production of complex pharmaceutical molecules.

Basic Information

Product Name	3'-Deamino-3'-Hydroxydaunorubicin
CAS No.	95405-79-1
Molecular Formula	C₂₇H₂₉NO₁₀
Molecular Weight	527.52 g/mol
Synonyms	3'-Deamino-3'-hydroxy-13-dihydrodaunorubicin; 3'-Deamino-3'-hydroxydaunomycin; 3'-Deamino-3'-hydroxy-13-dihydrodaunomycin; 3'-Deamino-3'-hydroxydaunorubicin hydrochloride (salt form); 3'-OH-3'-deaminodaunorubicin; IDA-3; A derivative of Idarubicin.
EINECS	Contact for details

Quality Control

Our 3'-Deamino-3'-Hydroxydaunorubicin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and MS, and residual solvent analysis, to ensure it meets the stringent requirements for pharmaceutical research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) or as specified on the label or COA. This product is light-sensitive and easily oxidized; prolonged exposure to air, light, or moisture should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	Red to orange-red powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.