Description

1',2'-Dihydro-1'-6-Dihydroxyrotenone is a specific derivative of the natural compound rotenone, characterized by its dihydro and dihydroxy modifications. This compound is of significant interest in biochemical and pharmacological research due to its structural relationship to rotenone, a well-known mitochondrial complex I inhibitor. It serves as a valuable analytical reference standard and a key intermediate for researchers in the fields of agrochemical development, natural product chemistry, and neurotoxicology. Industrial and academic laboratories utilize this high-purity compound for method development, quality control, and investigative studies.

Application

• Analytical Reference Standard: Used for the qualitative and quantitative analysis of rotenone derivatives in research and quality control laboratories.
• Biochemical Research: Serves as a tool compound for studying mitochondrial function, electron transport chain inhibition, and mechanisms of neurotoxicity.
• Agrochemical Intermediate: Acts as a key synthetic precursor or model compound in the development of novel, targeted botanical insecticides and acaricides.
• Natural Product Chemistry: Employed in studies investigating the structure-activity relationships (SAR) of rotenoids and their biological effects.
• Pharmaceutical Research: Investigated for its potential pharmacological properties and as a probe in metabolic pathway studies.

Basic Information

Product Name	1',2'-Dihydro-1'-6-Dihydroxyrotenone
CAS No.	95397-29-8
Molecular Formula	C23H22O7
Molecular Weight	410.42 g/mol
Synonyms	1',2'-Dihydro-1',6-dihydroxyrotenone; 6-Hydroxy-1',2'-dihydrodeguelin; (6aS,12aS,1'R)-1',2'-Dihydro-1',6-dihydroxy-12a-hydroxyrotenone; Dihydrodihydroxyrotenone; Rotenone derivative; Rotenoid intermediate
EINECS	Contact for details

Quality Control

Our 1',2'-Dihydro-1'-6-Dihydroxyrotenone is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is subjected to comprehensive analytical testing, including HPLC for purity assessment and spectroscopic methods (NMR, MS) for structural confirmation. A Certificate of Analysis (COA) detailing all test results and specifications is provided with every shipment to support your research and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.