Description

4-Carboxyethylphenylglyoxal-Bis(n-Methylthiosemicarbazone) is a specialized organic compound with a complex molecular structure featuring a phenylglyoxal core functionalized with thiosemicarbazone and carboxyethyl groups. This compound is significant for its potential as a versatile chelating agent and a key intermediate in the synthesis of advanced materials and pharmaceuticals. It is primarily needed by researchers and manufacturers in the fields of medicinal chemistry, radiopharmaceutical development, and as a precursor for metal-organic frameworks (MOFs) and other coordination polymers.

Application

• Radiopharmaceutical Precursor: Acts as a bifunctional chelator for labeling biomolecules with diagnostic or therapeutic radioisotopes (e.g., Technetium-99m, Copper-64).
• Medicinal Chemistry Intermediate: Serves as a key building block in the synthesis of novel drug candidates, particularly those targeting metal-dependent enzymes or requiring metal complexation.
• Coordination Chemistry Research: Used in academic and industrial R&D to study the formation and properties of transition metal complexes.
• Material Science: Employed as an organic linker or precursor in the fabrication of metal-organic frameworks (MOFs) for catalysis, gas storage, or sensing applications.
• Analytical Reagent: Functions as a selective complexing agent in spectrophotometric or fluorometric assays for metal ion detection.
• Chemical Synthesis: Utilized in organic synthesis to introduce specific functional groups or create complex molecular architectures.

Basic Information

Product Name	4-Carboxyethylphenylglyoxal-Bis(n-Methylthiosemicarbazone)
CAS No.	95297-83-9
Molecular Formula	C16H22N8O3S2
Molecular Weight	438.53 g/mol
Synonyms	4-(2-Carboxyethyl)phenylglyoxal-Bis(N-methylthiosemicarbazone); 4-Carboxyethylphenylglyoxal-Bis(N-methylthiosemicarbazone); 4-(2-Carboxyethyl)benzoylformaldehyde Bis(N-methylthiosemicarbazone); Glyoxal, 2-[4-(2-carboxyethyl)phenyl]-, bis[N-methylthiosemicarbazone]; Phenylglyoxal derivative thiosemicarbazone; Bifunctional chelator 95297-83-9; H2ATSM/ATSM precursor analog
EINECS	Contact for details

Quality Control

Our 4-Carboxyethylphenylglyoxal-Bis(n-Methylthiosemicarbazone) is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with data from advanced techniques such as HPLC, NMR, and mass spectrometry. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable performance in critical research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under anhydrous conditions, such as in a desiccator or under an inert atmosphere, to prevent degradation.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.