Description

5-[[2-Amino-4-Hydroxy-4-(5-Hydroxypyridin-2-Yl)-1-Oxobutyl]Amino]-1-(3,4-Dihydro-2,4-Dioxopyrimidin-1(2H)-Yl)-1,5-Dideoxy-β-D-Allofuranuronic Acid is a sophisticated nucleoside analog derivative with significant potential in advanced pharmaceutical research and development. Its complex structure, featuring both pyrimidine and pyridine moieties, makes it a valuable intermediate for designing novel therapeutic agents, particularly in antiviral and anticancer applications. This high-purity compound is essential for research institutions and pharmaceutical companies focused on nucleotide-based drug discovery and biochemical mechanism studies.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel nucleoside analog drugs targeting viral replication and cancer cell proliferation.
• Antiviral Drug Research: Used in the development of next-generation antiviral agents, particularly for viruses where nucleotide analogs are a primary therapeutic strategy.
• Oncology Research: Investigated as a precursor for chemotherapeutic agents designed to interfere with DNA/RNA synthesis in malignant cells.
• Biochemical Tool Compound: Employed in enzymatic studies to understand the interaction and inhibition of polymerases and other nucleic acid-processing enzymes.
• Preclinical Development: Utilized in the early-stage development and optimization of lead compounds for pharmacokinetic and pharmacodynamic studies.
• Academic Research: A key reagent for universities and research institutes exploring the structure-activity relationships of modified nucleosides.

Basic Information

Product Name	5-[[2-Amino-4-Hydroxy-4-(5-Hydroxypyridin-2-Yl)-1-Oxobutyl]Amino]-1-(3,4-Dihydro-2,4-Dioxopyrimidin-1(2H)-Yl)-1,5-Dideoxy-β-D-Allofuranuronic Acid
CAS No.	95259-47-5
Molecular Formula	C19H23N5O10
Molecular Weight	481.42 g/mol
Synonyms	1,5-Dideoxy-5-[[2-amino-4-hydroxy-4-(5-hydroxy-2-pyridinyl)-1-oxobutyl]amino]-1-(3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinyl)-β-D-allofuranuronic acid; β-D-Allofuranuronic acid derivative with CAS 95259-47-5; Nucleoside analog intermediate 95259-47-5; 5-(2-Amino-4-hydroxy-4-(5-hydroxypyridin-2-yl)-1-oxobutyl)amino-1-(3,4-dihydro-2,4-dioxopyrimidin-1(2H)-yl)-1,5-dideoxy-β-D-allofuranuronic acid; Modified Uridine Derivative; Pyridine-Pyrimidine Hybrid Nucleoside
EINECS	Contact for details

Quality Control

Our 5-[[2-Amino-4-Hydroxy-4-(5-Hydroxypyridin-2-Yl)-1-Oxobutyl]Amino]-1-(3,4-Dihydro-2,4-Dioxopyrimidin-1(2H)-Yl)-1,5-Dideoxy-β-D-Allofuranuronic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical research. Certificates of Analysis (COA) detailing purity, related substances, and other critical parameters are provided and available upon request to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic (moisture-sensitive) nature, store under controlled room temperature (15-25°C) in a dry environment. For long-term storage, consider desiccants or inert atmosphere to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Purity (HPLC, Area %)	≥ 98.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.