Description

5-[[2-Amino-4-Hydroxy-1-Oxo-4-(2-Pyridinyl)Butyl]Amino]-1-(3,4-Dihydro-2,4-Dioxopyrimidin-1(2H)-Yl)-1,5-Dideoxy-β-D-Allofuranuronic Acid is a sophisticated nucleoside analog derivative with a complex molecular architecture designed for targeted biochemical interactions. This compound is of significant value in advanced pharmaceutical research and development, particularly in the design of novel antiviral and anticancer therapeutic agents. It is primarily sought by R&D laboratories and pharmaceutical manufacturers engaged in the synthesis of modified nucleosides for probing biological mechanisms or developing active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel nucleoside-based antiviral and anticancer drug candidates.
• Biochemical Research: Used as a specialized substrate or inhibitor in enzymatic studies to investigate nucleotide metabolism and related pathways.
• Proteomics & Molecular Biology: Employed in the development of probes for studying nucleic acid-protein interactions and cellular signaling processes.
• Preclinical Development: Utilized in the early-stage development and optimization of therapeutic compounds targeting viral polymerases or cellular replication machinery.
• Academic Research: A key reagent for universities and research institutes exploring the structure-activity relationships (SAR) of modified nucleosides.
• Reference Standard: Supplied as a high-purity compound for use as an analytical standard in quality control and method development for related APIs.

Basic Information

Product Name	5-[[2-Amino-4-Hydroxy-1-Oxo-4-(2-Pyridinyl)Butyl]Amino]-1-(3,4-Dihydro-2,4-Dioxopyrimidin-1(2H)-Yl)-1,5-Dideoxy-β-D-Allofuranuronic Acid
CAS No.	95259-45-3
Molecular Formula	C18H22N6O8
Molecular Weight	450.41 g/mol
Synonyms	1,5-Dideoxy-1-[3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinyl]-5-[[2-amino-4-hydroxy-1-oxo-4-(2-pyridinyl)butyl]amino]-β-D-allofuranuronic acid; 5-[[2-Amino-4-hydroxy-1-oxo-4-(2-pyridinyl)butyl]amino]-1-(3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinyl)-1,5-dideoxy-β-D-allofuranuronic acid; β-D-Allofuranuronic acid derivative with CAS 95259-45-3; Nucleoside analog intermediate; Pyrimidine nucleoside derivative.
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Each batch undergoes comprehensive analytical characterization using techniques including HPLC, NMR, and mass spectrometry to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific client requirements for research or cGMP-grade material.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.