Description

8-Methoxyfenoldopam is a selective dopamine D1 receptor agonist and a key chemical intermediate in pharmaceutical research and development. This compound is of significant interest for its role in the synthesis of novel therapeutic agents targeting cardiovascular and renal systems. It is primarily utilized by pharmaceutical companies, contract research organizations (CROs), and academic institutions engaged in drug discovery and preclinical studies. Our supply ensures high purity and consistency, critical for reliable experimental outcomes and process development.

Application

• Pharmaceutical intermediate for the synthesis of dopamine receptor agonists.
• Reference standard in analytical method development and validation for pharmacokinetic studies.
• Key building block in medicinal chemistry research for cardiovascular drug candidates.
• Biochemical tool for in vitro pharmacological assays targeting D1 receptor pathways.
• Precursor in the development of potential treatments for hypertension and congestive heart failure.
• Used in academic and industrial research to study renal hemodynamics and natriuresis.

Basic Information

Product Name	8-Methoxyfenoldopam
CAS No.	95183-48-5
Molecular Formula	C16H16ClNO4
Molecular Weight	321.75 g/mol
Synonyms	SKF-82526; Fenoldopam 8-Methyl Ether; 6-Chloro-2,3,4,5-tetrahydro-1-(4-hydroxy-3-methoxyphenyl)-1H-3-benzazepine-7,8-diol 8-Methyl Ether; (6-Chloro-2,3,4,5-tetrahydro-1-(4-hydroxy-3-methoxyphenyl)-1H-3-benzazepine-7,8-diol) 8-Methyl Ether; 1-(4-Hydroxy-3-methoxyphenyl)-6-chloro-7,8-dihydroxy-2,3,4,5-tetrahydro-1H-3-benzazepine 8-Methyl Ether
EINECS	Contact for details

Quality Control

Our 8-Methoxyfenoldopam is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.