Description

7-Methoxyfenoldopam is a key chemical intermediate and research compound of significant interest in pharmaceutical development. Its primary value lies in its structural relationship to Fenoldopam, a potent dopamine receptor agonist, making it a crucial building block for synthesizing novel therapeutic agents. This compound is essential for research laboratories and pharmaceutical manufacturers focused on cardiovascular and renal drug discovery, as well as for the synthesis of specialized reference standards.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of Fenoldopam and its structural analogs for cardiovascular applications.
• Research & Development: Used as a reference standard and building block in medicinal chemistry for studying dopamine D1-like receptor activity and developing new receptor ligands.
• Active Pharmaceutical Ingredient (API) Synthesis: Serves as a key synthon in the production pathway for potential new chemical entities targeting hypertension and renal function.
• Biochemical Research: Employed in pharmacological studies to investigate vasodilation mechanisms and renal hemodynamics.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-purity advanced intermediates.

Basic Information

Product Name	7-Methoxyfenoldopam
CAS No.	95183-47-4
Molecular Formula	C16H16ClNO4
Molecular Weight	321.75 g/mol
Synonyms	6-Chloro-2,3,4,5-tetrahydro-7,8-dihydroxy-1-(4-methoxyphenyl)-1H-3-benzazepine; Fenoldopam 7-Methyl Ether; 7-O-Methylfenoldopam; SKF-82526-J; 1-(4-Methoxyphenyl)-6-chloro-7,8-dihydroxy-2,3,4,5-tetrahydro-1H-3-benzazepine
EINECS	Contact for details

Quality Control

Our 7-Methoxyfenoldopam is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and pharmaceutical synthesis. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to cGMP principles where applicable, and our quality standards are designed to meet the stringent requirements of pharmaceutical intermediate applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The compound may be light-sensitive and hygroscopic; therefore, containers should be kept sealed in a dry environment and handled under inert atmosphere when appropriate for long-term stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines
Loss on Drying	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.