Description

4-(((((3,5-Diamino-6-Chloropyrazinyl)Carbonyl)Amino)Iminomethyl)Amino)-2,2,6,6-Tetramethyl-1-Piperidinyloxy is a high-purity, stable nitroxide radical derivative with a complex heterocyclic structure. This compound is valued for its role as a spin label and probe in advanced spectroscopic research, particularly in electron paramagnetic resonance (EPR) studies. It is primarily utilized by research institutions, pharmaceutical developers, and specialty chemical manufacturers engaged in biophysical chemistry, materials science, and the study of molecular dynamics.

Application

• Spin Labeling in EPR Spectroscopy: Used as a stable radical probe to study the structure, dynamics, and conformational changes of proteins, nucleic acids, and synthetic polymers.
• Biophysical Research: Employed to investigate membrane fluidity, protein folding, and site-directed spin labeling (SDSL) experiments.
• Materials Science: Serves as a building block or dopant in the development of advanced materials, including organic magnets and conductive polymers.
• Pharmaceutical R&D: Utilized in drug discovery to probe drug-target interactions and to study the local environment within biological systems.
• Oxidation Catalyst Intermediate: Acts as a precursor or stable radical catalyst in controlled oxidation reactions for fine chemical synthesis.
• Polymer Chemistry: Functions as a radical initiator or stabilizer in controlled radical polymerization processes.

Basic Information

Product Name	4-(((((3,5-Diamino-6-Chloropyrazinyl)Carbonyl)Amino)Iminomethyl)Amino)-2,2,6,6-Tetramethyl-1-Piperidinyloxy
CAS No.	94696-78-3
Molecular Formula	C15H24ClN9O2
Molecular Weight	397.87 g/mol
Synonyms	4-(((((3,5-Diamino-6-chloropyrazine-2-carbonyl)amino)iminomethyl)amino)-2,2,6,6-tetramethylpiperidin-1-oxyl; 4-Amino-TEMPO-pyrazine derivative; 4-AT-Pyz; Nitroxide radical pyrazine conjugate; 1-Oxyl-2,2,6,6-tetramethyl-4-((((3,5-diamino-6-chloropyrazinyl)carbonyl)amino)iminomethyl)aminopiperidine; TEMPO-Pyrazine probe; EPR spin label 94696-78-3
EINECS	Contact for details

Quality Control

Our production of this advanced spin label adheres to stringent quality protocols to ensure high purity and batch-to-batch consistency, critical for sensitive research applications. Each lot undergoes comprehensive analysis, including HPLC for purity, EPR spectroscopy for radical content verification, and elemental analysis. A detailed Certificate of Analysis (COA) documenting identity, purity, and specific tests is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). For long-term stability, consider storage under an inert atmosphere such as argon or nitrogen. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Orange to red crystalline powder
Identification (IR)	Conforms to structure
Identification (EPR)	Characteristic nitroxide radical signal
Purity (HPLC)	≥ 97.0%
Radical Content (EPR)	≥ 95%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.