Description

(+/-)-2-(Aminoethyl)-12-Crown-4 is a functionalized crown ether derivative that serves as a versatile chelating agent and phase-transfer catalyst. Its primary value lies in its ability to selectively bind alkali and alkaline earth metal cations, particularly lithium ions, making it a critical component in advanced separation and sensing technologies. This compound is essential for researchers and manufacturers in the fields of lithium extraction, ion-selective electrodes, and organic synthesis, where precise metal ion recognition and transport are required.

Application

• Lithium Ion Selective Electrodes (ISE): A key component in membrane formulations for the potentiometric detection and quantification of lithium ions in clinical and environmental samples.
• Lithium Extraction & Separation: Used as a selective ionophore in liquid-liquid extraction systems and supported liquid membranes for the recovery and purification of lithium from brines and ores.
• Phase-Transfer Catalysis (PTC): Facilitates reactions between reagents in immiscible phases, particularly useful in nucleophilic substitution and alkylation reactions in organic synthesis.
• Chemical Sensors & Biosensors: Incorporated into sensor matrices for the development of selective and sensitive detection platforms for metal cations.
• Polymer-Modified Electrolytes: Acts as an additive in solid polymer electrolytes to enhance lithium ion conductivity and transport number in battery research.
• Analytical Chemistry Reagent: Employed in chromatographic and spectroscopic methods for the complexation and separation of metal ions.
• Supramolecular Chemistry Building Block: Serves as a precursor for constructing more complex host-guest systems and molecular machines.

Basic Information

Product Name	(+/-)-2-(Aminoethyl)-12-Crown-4
CAS No.	94616-61-2
Molecular Formula	C10H21NO4
Molecular Weight	219.28 g/mol
Synonyms	2-(2-Aminoethyl)-12-crown-4; 12-Crown-4, 2-(aminoethyl)-; 2-Aminoethyl-12-crown-4; Aminoethyl-12-crown-4; 1-Aza-4,7,10,13-tetraoxacyclopentadecane, 2-(2-aminoethyl)-; N-(2-(12-Crown-4))ethylamine; AE12C4; 2-(2-Aminoethyl)-1,4,7,10-tetraoxacyclododecane
EINECS	Contact for details

Quality Control

Our (+/-)-2-(Aminoethyl)-12-Crown-4 is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR for structural confirmation, and titration for functional group analysis, to ensure it meets the high standards required for research and industrial applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and assay is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation and maintain purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.