Description

(17-Alpha)-3,3-[(2,2-Dimethylpropane-1,3-Diyl)Bis(Oxy)]-17-Hydroxyandrost-5-Ene-17-Carbonitrile is a high-purity steroidal nitrile derivative, a key advanced pharmaceutical intermediate (API) in the synthesis of complex therapeutic agents. Its value lies in its precise molecular structure, which serves as a critical building block for developing novel steroid-based pharmaceuticals. This compound is essential for research and development laboratories, pharmaceutical manufacturers, and fine chemical producers focused on endocrinology, oncology, and metabolic disease treatments.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of potent steroidal drugs and hormone analogs.
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the development of new therapeutic candidates targeting steroid receptors.
• Fine Chemical Synthesis: Serves as a specialized building block for creating complex molecules in custom synthesis and contract manufacturing.
• Biochemical Research: Employed in biochemical assays and as a reference standard to study enzyme inhibition or receptor binding mechanisms.
• Academic Research: Utilized in university and institutional labs for advanced organic synthesis projects and pharmacological studies.

Basic Information

Product Name	(17-Alpha)-3,3-[(2,2-Dimethylpropane-1,3-Diyl)Bis(Oxy)]-17-Hydroxyandrost-5-Ene-17-Carbonitrile
CAS No.	94291-96-0
Molecular Formula	C₂₆H₃₉NO₃
Molecular Weight	413.60 g/mol
Synonyms	17-Hydroxy-3,3-[(2,2-dimethyltrimethylene)dioxy]androst-5-en-17-carbonitrile; 17α-Hydroxy-3,3-(2,2-dimethyltrimethylenedioxy)androst-5-en-17-carbonitrile; Androst-5-ene-17-carbonitrile, 17-hydroxy-3,3-[(2,2-dimethyl-1,3-propanediyl)bis(oxy)]-, (17α)-; 94291-96-0; Steroidal Nitrile Intermediate; 17-Cyano Steroid Derivative
EINECS	Contact for details

Quality Control

Our (17-Alpha)-3,3-[(2,2-Dimethylpropane-1,3-Diyl)Bis(Oxy)]-17-Hydroxyandrost-5-Ene-17-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical intermediate applications. Certificates of Analysis (COA) detailing purity, related substances, and residual solvents are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.