Description

[3R-(3Alpha,3Abeta,7Beta,8Aalpha)]-1-(2,3,4,7,8,8A-Hexahydro-3,8,8-Trimethyl-1H-3A,7-Methanoazulen-6-Yl)Acetone is a high-purity, complex sesquiterpenoid derivative with a distinctive methanoazulene core structure. This compound is valued for its role as a key chiral intermediate and building block in advanced organic synthesis, particularly for the development of fine chemicals and active pharmaceutical ingredients (APIs). It is essential for R&D and production teams in the pharmaceutical, agrochemical, and fragrance industries seeking to create novel molecules with specific stereochemical configurations.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of complex drug candidates, especially in steroid and terpenoid-based therapeutic research.
• Agrochemical Synthesis: Used in the development of novel pesticides and herbicides where its unique carbon skeleton imparts specific biological activity.
• Fragrance & Flavor Ingredient: Serves as a precursor for high-value aroma chemicals and fixatives in premium perfumery and flavor formulations.
• Organic Synthesis Building Block: Employed in academic and industrial laboratories for constructing complex polycyclic frameworks and exploring new chemical spaces.
• Material Science Research: Investigated as a monomer or precursor for specialty polymers and advanced organic materials with specific optical or electronic properties.

Basic Information

Product Name	[3R-(3Alpha,3Abeta,7Beta,8Aalpha)]-1-(2,3,4,7,8,8A-Hexahydro-3,8,8-Trimethyl-1H-3A,7-Methanoazulen-6-Yl)Acetone
CAS No.	94135-49-6
Molecular Formula	C18H26O
Molecular Weight	258.40 g/mol
Synonyms	6-(3-Oxobutyl)-1,2,3,4,7,8-hexahydro-3,8,8-trimethyl-1,4-methanoazulene; (3R,3aS,7R,8aR)-1-(2,3,4,7,8,8a-Hexahydro-3,8,8-trimethyl-1H-3a,7-methanoazulen-6-yl)ethan-1-one; 3a,7-Methanoazulene-6-acetone derivative; Hexahydrotrimethylmethanoazulenyl acetone; Sesquiterpenoid ketone intermediate
EINECS	Contact for details

Quality Control

Every batch of [3R-(3Alpha,3Abeta,7Beta,8Aalpha)]-1-(2,3,4,7,8,8A-Hexahydro-3,8,8-Trimethyl-1H-3A,7-Methanoazulen-6-Yl)Acetone is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including chiral purity analysis, to ensure compliance with research and pharmaceutical-grade standards. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided to guarantee batch-to-batch consistency and traceability for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its properties of being easily oxidized and highly volatile, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation and to minimize degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.