Description

2-(1,1-Dimethyl-2-Phenylethyl)-1,3-Dioxane is a specialized organic compound featuring a dioxane ring substituted with a bulky, aromatic neopentyl-like group. This unique structure makes it a valuable intermediate and building block in advanced organic synthesis, particularly for creating complex molecules with specific steric and electronic properties. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty materials industries for applications requiring tailored molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block or protecting group precursor in the synthesis of active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides, leveraging its sterically hindered structure.
• Ligand and Catalyst Development: Acts as a precursor for synthesizing specialized ligands used in asymmetric catalysis and transition metal complexes.
• Fragrance and Flavor Chemistry: Potential intermediate for creating unique aromatic compounds with modified stability and release profiles.
• Polymer Modification: Employed to introduce bulky pendant groups into polymer chains, altering physical properties like glass transition temperature and solubility.
• Organic Electronic Materials: Investigated as a component or precursor in the development of organic semiconductors and charge-transport materials.

Basic Information

Product Name	2-(1,1-Dimethyl-2-Phenylethyl)-1,3-Dioxane
CAS No.	93893-54-0
Molecular Formula	C14H20O2
Molecular Weight	220.31 g/mol
Synonyms	2-(2-Phenyl-2-propyl)-1,3-dioxane; 2-(α,α-Dimethylbenzyl)-1,3-dioxane; 2-(1,1-Dimethyl-2-phenylethyl)-1,3-dioxolane (common misnomer); 2-(2-Phenylpropan-2-yl)-1,3-dioxane; NSC 403120; 1,3-Dioxane, 2-(1,1-dimethyl-2-phenylethyl)-; 2-(Dimethylphenylmethyl)-1,3-dioxane
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for all our chemical intermediates. Production of 2-(1,1-Dimethyl-2-Phenylethyl)-1,3-Dioxane is monitored through in-process controls and final release testing, which typically includes identity confirmation, purity assay, and impurity profiling. A comprehensive Certificate of Analysis (COA) detailing batch-specific results is provided with every shipment. We can support development and commercial projects requiring compliance with cGMP, ICH guidelines, and other relevant regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC/HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.