Description

Neo-Gambogic Acid CAS NO 93772-31-7 is a bioactive xanthonoid compound derived from the resin of the Garcinia hanburyi tree. This high-purity reference standard is critical for pharmaceutical research and development, particularly in the study of novel anticancer and anti-inflammatory agents. It is primarily sought by research institutions, pharmaceutical companies, and manufacturers of high-grade botanical extracts for use in analytical testing, bioactivity screening, and as a key intermediate in drug discovery pipelines.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for the quality control and quantification of gambogic acid derivatives in raw materials and finished products.
• Anticancer Research: Serves as a lead compound and biochemical tool in preclinical studies investigating apoptosis induction, cell cycle arrest, and inhibition of tumor growth.
• Anti-inflammatory Agent Development: Employed in research targeting NF-κB and other inflammatory pathways for the development of new therapeutic agents.
• Natural Product Chemistry: Acts as a key intermediate or target molecule for the synthesis, semi-synthesis, and structural modification of novel xanthonoids.
• Analytical Method Development: Essential for developing and validating HPLC, LC-MS, and other chromatographic methods for the analysis of Garcinia extracts.
• Biochemical & Pharmacological Screening: Used in high-throughput screening (HTS) assays to evaluate biological activity and mechanism of action.

Basic Information

Product Name	Neo-Gambogic Acid
CAS No.	93772-31-7
Molecular Formula	C38H44O9
Molecular Weight	668.8 g/mol
Synonyms	Neogambogic Acid; Gambogic Acid Isomer; (1S,5R,7R,8S)-8-Hydroxy-4,4,7,10-tetramethyl-13-oxo-3,14-dioxatetracyclo[9.3.1.01,5.07,9]pentadec-10-ene-8-carboxylic Acid; Garcinia Acid Derivative; 1,3,5-Trihydroxy-13,13-dimethyl-11-(3-methylbut-2-en-1-yl)-2,10-dioxatricyclo[7.3.1.03,7]trideca-4,6-diene-8,12-dione
EINECS	Contact for details

Quality Control

Our Neo-Gambogic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR and MS for identification, and residual solvent analysis, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and light-sensitive; desiccants are recommended for long-term storage. Keep container tightly sealed under an inert atmosphere when not in use to maintain stability.

Specification

Item	Specification
Appearance	Yellow to orange powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.