Description

(+)-Taddol CAS NO 93379-49-8 is a highly versatile and enantiomerically pure chiral ligand and Brønsted acid catalyst. Its significance lies in its ability to induce high stereoselectivity in a wide range of organic transformations, making it a cornerstone for advanced synthetic chemistry. This product is essential for research and development laboratories, fine chemical synthesis, and pharmaceutical manufacturing where precise control over molecular chirality is required.

Application

• Asymmetric Catalysis: A key ligand for titanium, aluminum, and zinc complexes in enantioselective additions, such as the diethylzinc addition to aldehydes.
• Chiral Resolution: Used as a resolving agent for the separation of racemic mixtures of alcohols, amines, and other functional compounds.
• Pharmaceutical Intermediates: Critical in the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs) and complex natural products.
• Organocatalysis: Functions as a chiral Brønsted acid catalyst for promoting stereoselective reactions like hetero-Diels–Alder and Friedel–Crafts alkylations.
• Material Science Research: Employed in the development of chiral stationary phases for chromatography and chiral molecular recognition systems.
• Academic & Industrial R&D: A fundamental tool for methodological development in synthetic organic chemistry laboratories worldwide.

Basic Information

Product Name	(+)-Taddol
CAS No.	93379-49-8
Molecular Formula	C41H32O2
Molecular Weight	556.70 g/mol
Synonyms	(αR,α'R)-α,α'-Bis(trityloxy)-1,3-dioxolane-4,5-dimethanol; (R,R)-TADDOL; (4R,5R)-2,2-Dimethyl-α,α,α',α'-tetraphenyl-1,3-dioxolane-4,5-dimethanol; TADDOL ligand; (+)-α,α,α',α'-Tetraaryl-1,3-dioxolane-4,5-dimethanol; (R,R)-Tetraaryl-1,3-dioxolane-4,5-dimethanol derivative
EINECS	Contact for details

Quality Control

Our (+)-Taddol is manufactured under strict quality protocols to ensure high enantiomeric purity and chemical consistency, suitable for demanding synthetic applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing key parameters such as chiral purity, chemical assay, and impurity profile. We adhere to cGMP principles where applicable to support pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under an inert atmosphere for long-term storage to maintain optimal purity and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Melting Point	168 - 172 °C
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.