Description

3-Hydroxy-4,7,7-Trimethyl-Bicyclo[2.2.1]Heptane-1-Carboxylic Acid is a high-purity, functionalized bicyclic compound that serves as a valuable chiral building block and intermediate in advanced organic synthesis. Its unique sterically hindered structure and carboxylic acid functionality make it critical for constructing complex molecular architectures with precise stereochemistry. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where its bicyclic framework contributes to biological activity.
• Fine Chemical Production: Serves as a precursor for fragrances, flavors, and other high-value specialty chemicals requiring specific stereochemical configurations.
• Asymmetric Catalysis Ligand Precursor: Its structure can be modified to create novel chiral ligands for asymmetric hydrogenation and other catalytic processes.
• Material Science Research: Investigated as a monomer or additive for creating polymers with unique thermal or mechanical properties.
• Academic & Industrial R&D: A valuable tool for methodological development in organic synthesis and stereochemistry studies.

Basic Information

Product Name	3-Hydroxy-4,7,7-Trimethyl-Bicyclo[2.2.1]Heptane-1-Carboxylic Acid
CAS No.	93257-31-9
Molecular Formula	C11H18O3
Molecular Weight	198.26 g/mol
Synonyms	1-Carboxy-3-hydroxy-4,7,7-trimethylbicyclo[2.2.1]heptane; 3-Hydroxy-4,7,7-trimethyl-2-norbornanecarboxylic Acid; Trimethylbicycloheptanecarboxylic Acid Derivative; 4,7,7-Trimethyl-3-hydroxybicyclo[2.2.1]heptane-1-carboxylic Acid; HydroxytriMethylnorbornanecarboxylic Acid
EINECS	Contact for details

Quality Control

Our 3-Hydroxy-4,7,7-Trimethyl-Bicyclo[2.2.1]Heptane-1-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment to guarantee traceability, consistency, and reliability for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); containers must be kept tightly sealed to prevent absorption of atmospheric moisture, which may affect purity and stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee (by Chiral HPLC)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.