Description

Ethyl 4-(Tosyloxy)Cyclohexanecarboxylate is a high-value, multi-functional chemical intermediate featuring a cyclohexane ring system with both ester and tosylate leaving groups. This unique bifunctional structure makes it a versatile building block for synthesizing complex molecules in advanced pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists in the fine chemical and pharmaceutical industries for constructing novel active ingredients and exploring new synthetic pathways.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting the central nervous system (CNS) or requiring complex cyclohexane-based scaffolds.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and plant growth regulators where the tosylate group facilitates further functionalization.
• Advanced Material Research: Serves as a monomer or cross-linking agent in the development of specialty polymers and liquid crystals with specific optical or mechanical properties.
• Organic Synthesis Building Block: The reactive tosylate group enables nucleophilic substitution reactions, while the ester group can be hydrolyzed or reduced, offering multiple points for chemical modification.
• Catalyst and Ligand Development: Employed in the preparation of chiral auxiliaries or complex ligands for asymmetric catalysis.
• Custom Synthesis Projects: A critical starting material for contract research organizations (CROs) and CDMOs engaged in custom synthesis for client-specific molecular targets.

Basic Information

Product Name	Ethyl 4-(Tosyloxy)Cyclohexanecarboxylate
CAS No.	93164-43-3
Molecular Formula	C16H22O5S
Molecular Weight	326.41 g/mol
Synonyms	Ethyl 4-[(4-methylphenyl)sulfonyloxy]cyclohexanecarboxylate; 4-(Tosyloxy)cyclohexanecarboxylic Acid Ethyl Ester; Ethyl 4-(p-Toluenesulfonyloxy)cyclohexanecarboxylate; Cyclohexanecarboxylic acid, 4-[(4-methylphenyl)sulfonyl]oxy]-, ethyl ester; Ethyl trans-4-(Tosyloxy)cyclohexanecarboxylate (potential isomer)
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch of Ethyl 4-(Tosyloxy)Cyclohexanecarboxylate is analyzed using advanced techniques like HPLC, GC, and NMR to confirm identity, purity, and the absence of critical impurities. Certificates of Analysis (COA) with detailed chromatographic data are available upon request. We adhere to a quality management system suitable for supplying intermediates to cGMP-compliant environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.