Description

1-(p-Tosyloxy)-2-Pentyne is a specialized organic building block featuring a tosyl-protected propargylic alcohol moiety. This compound is valued for its role as a versatile intermediate in advanced organic synthesis, enabling the construction of complex molecular architectures. It is primarily sought by research and development chemists in the pharmaceutical, agrochemical, and advanced materials sectors for applications in cross-coupling reactions and the synthesis of bioactive molecules.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides.
• Material Science: Intermediate for creating specialized polymers and advanced organic materials with tailored properties.
• Cross-Coupling Reactions: Serves as a substrate in Sonogashira, Heck, and other palladium-catalyzed coupling reactions.
• Academic & Industrial R&D: A valuable reagent for methodological development and exploring new synthetic pathways in organic chemistry.
• Fine Chemical Production: Employed in the multi-step synthesis of complex fragrance and flavor compounds.

Basic Information

Product Name	1-(p-Tosyloxy)-2-Pentyne
CAS No.	92666-05-2
Molecular Formula	C₁₂H₁₄O₃S
Molecular Weight	238.30 g/mol
Synonyms	2-Pentyn-1-ol, 1-(4-methylbenzenesulfonate); 1-Tosyloxy-2-pentyne; p-Toluenesulfonic acid 2-pentyn-1-yl ester; 2-Pentyn-1-yl p-toluenesulfonate; 1-(4-Methylphenylsulfonyloxy)-2-pentyne; Propargyl tosylate derivative; C12H14O3S
EINECS	Contact for details

Quality Control

Our 1-(p-Tosyloxy)-2-Pentyne is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and industrial synthesis. Each lot is analyzed using advanced techniques including HPLC, GC, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 95% (Typical 97-99%)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.