Description

Bicyclo[2.2.1]Hept-5-Ene-2-Carboxylic Acid, 2-Methyl-, (1S-Exo)- (9Ci) is a high-purity, stereochemically defined bicyclic carboxylic acid derivative, serving as a critical chiral building block in advanced organic synthesis. Its rigid, functionalized norbornene framework offers unique steric and electronic properties for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries, particularly for developing novel active pharmaceutical ingredients (APIs) and specialty materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of complex drug molecules, especially those requiring the specific (1S-Exo) stereochemistry.
• Asymmetric Catalysis Ligand Precursor: Used to develop novel chiral ligands and organocatalysts for enantioselective transformations.
• Polymer Science Monomer: Acts as a functional monomer for creating specialty polymers with tailored thermal and mechanical properties via ring-opening metathesis polymerization (ROMP).
• Agrochemical Synthesis: Employed in the research and development of advanced, stereospecific pesticides and herbicides.
• Material Science Research: Utilized in the design of advanced organic materials, including liquid crystals and nonlinear optical (NLO) materials.
• Academic & R&D Laboratories: Serves as a valuable reagent for methodological development in organic chemistry and total synthesis projects.

Basic Information

Product Name	Bicyclo[2.2.1]Hept-5-Ene-2-Carboxylic Acid, 2-Methyl-, (1S-Exo)- (9Ci)
CAS No.	92007-58-4
Molecular Formula	C9H12O2
Molecular Weight	152.19 g/mol
Synonyms	(1S-exo)-2-Methylbicyclo[2.2.1]hept-5-ene-2-carboxylic acid; exo-2-Methyl-5-norbornene-2-carboxylic acid; 2-Methyl-2-norbornene-5-exo-carboxylic acid; 2-Methylbicyclo[2.2.1]hept-5-ene-2-carboxylic acid, (1S-exo)-; 2-Norbornene-2-carboxylic acid, 2-methyl-, exo-; (1S,2R,4S)-2-Methylbicyclo[2.2.1]hept-5-ene-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our Bicyclo[2.2.1]Hept-5-Ene-2-Carboxylic Acid, 2-Methyl-, (1S-Exo)- (9Ci) is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high chemical purity. Production adheres to cGMP guidelines where applicable, and each lot is supported by a comprehensive Certificate of Analysis (COA). The COA includes data for chiral purity, chemical assay, and impurity profile, meeting the stringent requirements of pharmaceutical R&D and production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and organic solvents. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (1S-exo)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.