Description

2-Butanone, 1-Chloro-1-Fluoro-3,3-Dimethyl- is a specialized fluorinated ketone building block, offering a unique combination of reactivity and structural features for advanced chemical synthesis. Its value lies in providing a versatile scaffold for introducing both fluorine and chlorine substituents, which are critical for modulating the physical and biological properties of target molecules. This compound is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors seeking to develop novel compounds with enhanced performance characteristics.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the development of active pharmaceutical ingredients (APIs), particularly for introducing fluorinated motifs known to improve metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the halogenated structure can enhance pesticidal activity and environmental persistence.
• Advanced Material Precursor: Acts as a monomer or cross-linking agent in the synthesis of specialty polymers, coatings, and liquid crystals with tailored thermal and chemical resistance.
• Organic Synthesis Building Block: Employed in academic and industrial laboratories for constructing complex organic molecules, leveraging the ketone and halogen functional groups for further chemical transformations.
• Fluorine Chemistry Research: A valuable compound for studying structure-activity relationships (SAR) and developing new fluorination methodologies in medicinal and synthetic chemistry.

Basic Information

Product Name	2-Butanone, 1-Chloro-1-Fluoro-3,3-Dimethyl-
CAS No.	91524-21-9
Molecular Formula	C6H10ClFO
Molecular Weight	148.59 g/mol
Synonyms	1-Chloro-1-fluoro-3,3-dimethylbutan-2-one; 3,3-Dimethyl-1-chloro-1-fluorobutan-2-one; 1-Chloro-1-fluoro-3,3-dimethyl-2-butanone; 1-Fluoro-1-chloro-3,3-dimethylbutan-2-one; FC-3,3-Dimethyl Butanone Chloride (common name)
EINECS	Contact for details

Quality Control

Our 2-Butanone, 1-Chloro-1-Fluoro-3,3-Dimethyl- is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. We offer material suitable for research and development as well as scaled-up production needs. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is moisture-sensitive; ensure containers are kept tightly sealed to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.