Description

4-Iodonaphthalene-1-Carboxylic Acid is a high-value iodinated naphthalene derivative that serves as a versatile and critical building block in advanced organic synthesis. Its molecular structure, featuring both a carboxylic acid and an iodine substituent, makes it an essential precursor for constructing complex molecules, particularly in pharmaceutical and materials science research. This compound is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, especially for non-steroidal anti-inflammatory drugs (NSAIDs) and other bioactive molecules containing naphthalene cores.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and plant growth regulators.
• Material Science: Building block for organic semiconductors, liquid crystals, and advanced polymers due to the naphthalene scaffold's electronic properties.
• Cross-Coupling Reactions: The iodine atom makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille, Sonogashira) to form new carbon-carbon bonds.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized ligands used in homogeneous catalysis.
• Fluorescent Probe Synthesis: Utilized in the creation of fluorescent tags and molecular probes for biochemical and diagnostic applications.
• Academic & Industrial Research: A valuable reagent for methodological studies in organic chemistry and for exploring new synthetic pathways.

Basic Information

Product Name	4-Iodonaphthalene-1-Carboxylic Acid
CAS No.	91059-41-5
Molecular Formula	C11H7IO2
Molecular Weight	298.08 g/mol
Synonyms	1-Carboxy-4-iodonaphthalene; 4-Iodo-1-naphthoic Acid; 4-Iodo-1-naphthalenecarboxylic Acid; 1-Naphthalenecarboxylic acid, 4-iodo-; 4-Iodonaphthalene-1-carboxylic acid; 4-Iodo-1-naphthalenecarboxylic acid; 4-Iodo-1-naphthoic acid; 4-Iodonaphthalenecarboxylic acid
EINECS	Contact for details

Quality Control

Our 4-Iodonaphthalene-1-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and FT-IR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality parameters. Our commitment to quality supports your research and development needs with reliable, high-purity intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly closed in a dry and well-ventilated place.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residue on Ignition	< 0.1%
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.