Description

4-Acetamidocyclohexane-1-Carboxylic Acid is a versatile organic intermediate featuring both a carboxylic acid and an acetamide functional group on a cyclohexane ring. This bifunctional structure makes it a valuable building block for the synthesis of more complex molecules, particularly in pharmaceutical research and development. It is primarily sought after by fine chemical manufacturers and R&D laboratories engaged in creating novel active pharmaceutical ingredients (APIs), agrochemicals, and advanced materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and production of novel drug candidates, particularly those targeting neurological or metabolic pathways.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and plant growth regulators.
• Peptide Mimetics & Conformationally Restricted Analogs: The cyclohexane scaffold provides rigidity, making it useful for designing peptide analogs with enhanced stability and bioavailability.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands used in asymmetric synthesis and catalysis.
• Polymer Modification: Can be incorporated into polymer chains to modify thermal and mechanical properties.
• Academic & Industrial R&D: A fundamental building block for exploratory chemistry in medicinal and synthetic organic chemistry programs.

Basic Information

Product Name	4-Acetamidocyclohexane-1-Carboxylic Acid
CAS No.	90942-88-4
Molecular Formula	C9H15NO3
Molecular Weight	185.22 g/mol
Synonyms	4-(Acetylamino)cyclohexanecarboxylic Acid; trans-4-Acetamidocyclohexanecarboxylic Acid; 4-Acetamidocyclohexanecarboxylic Acid; 4-Acetamido-1-cyclohexanecarboxylic Acid; 4-Carboxycyclohexylacetamide; NSC 163031; Ac-4-Ach-OH
EINECS	Contact for details

Quality Control

Our production of 4-Acetamidocyclohexane-1-Carboxylic Acid adheres to strict in-process controls and final batch testing to ensure consistent high purity and chemical identity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, impurity profile, and physical characteristics. Our quality system is designed to meet the rigorous demands of GMP-aligned manufacturing for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed to prevent absorption of atmospheric moisture, which can affect purity and stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.