Description

n-Alloc-2-Nitrobenzenesulfonamide is a specialized, high-purity chemical intermediate designed for advanced organic synthesis. This compound is valued for its role as a protected amine synthon, where the Alloc (allyloxycarbonyl) group offers orthogonal deprotection strategies critical for complex, multi-step reactions. It is essential for researchers and process chemists in the pharmaceutical and agrochemical industries developing novel active ingredients, particularly in peptide mimetics and combinatorial chemistry.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex drug candidates, especially those requiring selective amine protection and deprotection sequences.
• Peptide Chemistry: Used in solid-phase and solution-phase peptide synthesis to introduce protected amino functionalities.
• Agrochemical Research: Serves as a precursor in the development of new herbicides, fungicides, and insecticides with novel modes of action.
• Chemical Biology & Proteomics: Employed in the design and synthesis of activity-based probes and bioconjugation reagents.
• Material Science: Potential monomer or cross-linking agent in the development of specialized polymers and functional materials.
• Academic & R&D Laboratories: A valuable reagent for methodological development in organic synthesis and catalysis studies.

Basic Information

Product Name	n-Alloc-2-Nitrobenzenesulfonamide
CAS No.	90916-29-3
Molecular Formula	C10H10N2O5S
Molecular Weight	270.26 g/mol
Synonyms	N-Alloc-2-nitrobenzenesulfonamide; Allyl (2-nitrophenylsulfonyl)carbamate; 2-Nitro-N-[(allyloxy)carbonyl]benzenesulfonamide; N-(Allyloxycarbonyl)-2-nitrobenzenesulfonamide; Alloc-Nosylamide; Nosyl-Alloc-protected amine; Allyloxycarbonyl 2-nitrobenzenesulfonamide
EINECS	Contact for details

Quality Control

Our n-Alloc-2-Nitrobenzenesulfonamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.