Description

Ethanone, 1-(9-Azabicyclo[4.2.1]non-2-yl)-, (1S-exo)- (9Ci) is a high-purity, stereochemically defined advanced pharmaceutical intermediate. This compound is valued for its role as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly those targeting the central nervous system. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of complex drug molecules, especially in neurological and psychiatric drug discovery.
• Organic Synthesis Research: Used in academic and industrial research for constructing novel nitrogen-containing bicyclic frameworks and studying structure-activity relationships.
• Asymmetric Catalysis: Serves as a precursor or ligand for developing chiral catalysts due to its rigid, stereodefined azabicyclic structure.
• Medicinal Chemistry: Employed in lead optimization and scaffold-hopping strategies to improve pharmacokinetic properties and biological activity of candidate compounds.
• Reference Standard: Used as a high-purity analytical standard for quality control and method development in API manufacturing.

Basic Information

Product Name	Ethanone, 1-(9-Azabicyclo[4.2.1]non-2-yl)-, (1S-exo)- (9Ci)
CAS No.	90821-02-6
Molecular Formula	C11H17NO
Molecular Weight	179.26 g/mol
Synonyms	(1S-exo)-1-(9-Azabicyclo[4.2.1]non-2-yl)ethanone; 1-(9-Azabicyclo[4.2.1]non-2-yl)ethan-1-one, (1S,2S,5R)-; exo-2-Acetyl-9-azabicyclo[4.2.1]nonane; 9-Azabicyclo[4.2.1]non-2-yl methyl ketone, (1S-exo)-; 90821-02-6; (1S-exo)-2-Acetyl-9-azabicyclo[4.2.1]nonane
EINECS	Contact for details

Quality Control

Our Ethanone, 1-(9-Azabicyclo[4.2.1]non-2-yl)-, (1S-exo)- (9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the stringent requirements for pharmaceutical development. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.