Description

(S)-tert-Butyl 2-((tert-Butoxycarbonyl)Amino)-5-Hydroxypentanoate is a high-purity, chiral amino acid derivative that serves as a critical building block in advanced organic synthesis. Its value lies in providing a protected, stereochemically defined scaffold for constructing complex peptide and peptidomimetic structures. This compound is essential for researchers and manufacturers in the pharmaceutical industry, particularly in the development of novel active pharmaceutical ingredients (APIs) and therapeutic peptides.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of peptide-based drugs and bioactive molecules.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis (SPPS) to introduce specific amino acid sequences with defined stereochemistry.
• API Development: Serves as a building block in the research and scale-up production of new active pharmaceutical ingredients.
• Protease Inhibitor Synthesis: A precursor in the construction of protease inhibitor candidates for therapeutic applications.
• Bioconjugation Chemistry: The hydroxyl and protected amine functionalities allow for selective modification and linker attachment.
• Chemical Biology Research: Used in the synthesis of labeled peptides and molecular probes for studying biological mechanisms.

Basic Information

Product Name	(S)-tert-Butyl 2-((tert-Butoxycarbonyl)Amino)-5-Hydroxypentanoate
CAS No.	90194-99-3
Molecular Formula	C14H27NO5
Molecular Weight	289.37 g/mol
Synonyms	Boc-L-Homoserine(tBu)-OH; (S)-2-((tert-Butoxycarbonyl)amino)-5-hydroxypentanoic acid tert-butyl ester; Boc-Hse(OtBu)-OH; Boc-L-Homoserine(OtBu)-OH; tert-Butyl (2S)-2-[(tert-butoxycarbonyl)amino]-5-hydroxypentanoate; (S)-5-Hydroxy-2-((tert-butoxycarbonyl)amino)pentanoic acid tert-butyl ester; Boc-Homoserine(tBu)-OH; L-Homoserine, N-(tert-butoxycarbonyl)-, 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our (S)-tert-Butyl 2-((tert-Butoxycarbonyl)Amino)-5-Hydroxypentanoate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for pharmaceutical research. We provide comprehensive analytical data, including HPLC purity, chiral purity, and identity confirmation. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.