Description

Methyl 1,3-Dihydroxycholan-24-Oate CAS NO 90134-61-5 is a high-purity bile acid derivative, specifically a methylated dihydroxy cholanate, serving as a critical intermediate in advanced pharmaceutical synthesis. This compound is valued for its defined stereochemistry and functional groups, which are essential for constructing complex steroid-based therapeutics and research compounds. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel drug candidates, particularly in the fields of hepatology, metabolic disorders, and hormone-related therapies.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel steroid-based drugs and therapeutic agents.
• Biochemical Research: Used as a reference standard or precursor in metabolic pathway studies and enzyme interaction research.
• Hepatology Research: Investigated for its role in bile acid metabolism and potential applications in liver disease models.
• Chemical Synthesis: Serves as a chiral starting material for the preparation of more complex, functionalized steroid derivatives.
• Academic & Industrial R&D: Employed in laboratories for method development and the discovery of new bioactive molecules.

Basic Information

Product Name	Methyl 1,3-Dihydroxycholan-24-Oate
CAS No.	90134-61-5
Molecular Formula	C₂₅H₄₂O₄
Molecular Weight	406.60 g/mol
Synonyms	Methyl 3α,7α-dihydroxy-5β-cholan-24-oate; Methyl 3α,7α-dihydroxy-5β-cholanate; 3α,7α-Dihydroxy-5β-cholan-24-oic acid methyl ester; Chenodeoxycholic acid methyl ester; Methyl chenodeoxycholate; CDCA methyl ester; Methyl 1,3-dihydroxycholanate
EINECS	Contact for details

Quality Control

Our Methyl 1,3-Dihydroxycholan-24-Oate is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including chromatographic purity assays and identity confirmation. A Certificate of Analysis (COA) detailing specific results for purity, related substances, and other critical parameters is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.