Description

(2R)-2-[Benzoyl-(3-Chloro-4-Fluoro-Phenyl)Amino]Propanoic Acid is a high-purity chiral intermediate of significant importance in advanced pharmaceutical synthesis. Its value lies in its role as a key building block for the development of enantiomerically pure active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring high specificity. This compound is essential for research institutions and manufacturers engaged in the development of novel small-molecule drugs, agrochemicals, and other fine chemicals where stereochemical control is critical.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon in the multi-step synthesis of enantiomerically pure Active Pharmaceutical Ingredients (APIs).
• Agrochemical Research: Serves as a building block for developing novel, stereospecific herbicides, fungicides, or insecticides.
• Chemical Biology & Proteomics: Used in the design and synthesis of molecular probes and enzyme inhibitors for target validation studies.
• Asymmetric Catalysis: May be employed as a precursor or ligand in the development of chiral catalysts.
• Academic & Contract Research: Utilized in university and CRO laboratories for methodological development in organic and medicinal chemistry.
• Fine Chemical Synthesis: Applied in the custom synthesis of complex, high-value specialty chemicals for various industrial applications.

Basic Information

Product Name	(2R)-2-[Benzoyl-(3-Chloro-4-Fluoro-Phenyl)Amino]Propanoic Acid
CAS No.	90134-59-1
Molecular Formula	C16H13ClFNO3
Molecular Weight	321.73 g/mol
Synonyms	(R)-2-(N-(3-Chloro-4-fluorophenyl)benzamido)propanoic acid; (2R)-2-[[(3-Chloro-4-fluorophenyl)amino](phenyl)carbonyl]propanoic acid; N-(3-Chloro-4-fluorophenyl)-N-benzoyl-D-alanine; D-N-(3-Chloro-4-fluorophenyl)benzoylalanine; 90134-59-1; Benzamide, N-(3-chloro-4-fluorophenyl)-N-(1-oxo-2-propanyl)-, (R)-; Propanoic acid, 2-[benzoyl(3-chloro-4-fluorophenyl)amino]-, (2R)-
EINECS	Contact for details

Quality Control

Our production of (2R)-2-[Benzoyl-(3-Chloro-4-Fluoro-Phenyl)Amino]Propanoic Acid adheres to stringent quality management systems to ensure batch-to-batch consistency and high purity suitable for research and GMP-grade synthesis. Each lot undergoes comprehensive analytical characterization, including chiral purity verification. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.