Description

Cyclohexanecarboxylic Acid, 2-Amino-3-Hydroxy- is a functionalized cyclohexane derivative that serves as a versatile chiral building block in advanced organic synthesis. Its unique structure, featuring both amino and hydroxyl groups on the cyclohexane ring, makes it a critical intermediate for constructing complex molecules with specific stereochemistry. This compound is particularly valuable for pharmaceutical research and development, where it is used in the synthesis of active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the production of active pharmaceutical ingredients (APIs), especially in cardiovascular and central nervous system (CNS) drug candidates.
• Asymmetric Synthesis: Used as a starting material or auxiliary in catalytic asymmetric reactions to introduce stereogenic centers.
• Peptidomimetics & Bioactive Molecule Development: Incorporated into the backbone of peptide analogs and other bioactive compounds to modulate their properties and stability.
• Agrochemical Research: Intermediate in the synthesis of novel herbicides, fungicides, and plant growth regulators with enhanced selectivity.
• Ligand & Catalyst Preparation: Serves as a precursor for chiral ligands used in transition metal catalysis.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic chemistry and medicinal chemistry programs.

Basic Information

Product Name	Cyclohexanecarboxylic Acid, 2-Amino-3-Hydroxy-
CAS No.	90129-19-4
Molecular Formula	C7H13NO3
Molecular Weight	159.18 g/mol
Synonyms	2-Amino-3-hydroxycyclohexanecarboxylic acid; (1R,2S,3R)-2-Amino-3-hydroxycyclohexanecarboxylic acid; 2-Amino-3-hydroxy-1-cyclohexanecarboxylic acid; AHCH; trans-2-Amino-cis-3-hydroxycyclohexanecarboxylic acid; β-Amino-γ-hydroxycyclohexanecarboxylic acid; 2-Amino-3-hydroxycyclohexane-1-carboxylic acid
EINECS	Contact for details

Quality Control

Our production of Cyclohexanecarboxylic Acid, 2-Amino-3-Hydroxy- adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and standard identification tests. We provide detailed Certificates of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or production specifications. Our quality systems are designed to support cGMP and ISO standards for reliable supply to regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to prevent moisture absorption, which can affect stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% e.e.
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.