Description

1-Bromo-5-Chloro-2-Methoxy-4-Methyl-Benzene is a high-purity halogenated anisole derivative, serving as a critical building block in advanced organic synthesis. Its precise substitution pattern makes it an invaluable intermediate for constructing complex molecular architectures, particularly in the pharmaceutical and agrochemical sectors. This compound is essential for researchers and manufacturers developing active pharmaceutical ingredients (APIs), liquid crystal materials, and specialty fine chemicals who require reliable access to high-quality, structurally defined intermediates.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, particularly for constructing complex aromatic cores in active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides, leveraging its halogen and methoxy functional groups.
• Liquid Crystal Materials: Serves as a precursor in the production of halogenated liquid crystal compounds for display technologies.
• Organic Electronic Materials: Employed in the research and development of organic semiconductors and charge-transport materials.
• Dye and Pigment Intermediate: Acts as a building block for synthesizing specialized halogenated dyes and pigments.
• Cross-Coupling Reactions: A valuable substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille) due to the bromo substituent.
• Chemical Research & Development: Used in academic and industrial R&D for exploring new synthetic methodologies and creating compound libraries.

Basic Information

Product Name	1-Bromo-5-Chloro-2-Methoxy-4-Methyl-Benzene
CAS No.	90004-78-7
Molecular Formula	C8H8BrClO
Molecular Weight	235.51 g/mol
Synonyms	2-Bromo-4-Chloro-5-Methoxytoluene; 4-Chloro-2-Bromo-5-Methoxytoluene; 5-Chloro-2-Bromo-4-Methylanisole; 1-Bromo-5-chloro-2-methoxy-4-methylbenzene; 2-Methoxy-4-methyl-1-bromo-5-chlorobenzene; Benzene, 1-bromo-5-chloro-2-methoxy-4-methyl-; Toluene, 2-bromo-4-chloro-5-methoxy-
EINECS	Contact for details

Quality Control

Our 1-Bromo-5-Chloro-2-Methoxy-4-Methyl-Benzene is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent quality suitable for demanding synthetic applications. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong bases and incompatible organic solvents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.