Description

2-tert-Butoxycarbonylamino-Propionic Acid is a protected amino acid derivative, specifically a Boc-protected alanine analog, serving as a crucial building block in organic synthesis. Its primary value lies in providing a robust, orthogonal protecting group for the amine functionality, enabling complex multi-step reactions in peptide and small molecule synthesis. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical industries who require reliable, high-quality reagents for advanced chemical development.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs) and novel drug candidates, particularly in peptide-based therapeutics.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis (SPPS) to incorporate alanine residues while protecting the amine group from unwanted side reactions.
• Protecting Group Chemistry: The tert-butoxycarbonyl (Boc) group is selectively introduced and removed under mild acidic conditions, facilitating complex multi-step synthetic routes.
• Bioconjugation & Linker Chemistry: Employed in the creation of chemical linkers and for modifying biomolecules in drug delivery system development.
• Fine Chemical Synthesis: Serves as a versatile chiral synthon for the production of specialty chemicals, catalysts, and ligands used in asymmetric synthesis.
• Academic & Industrial R&D: A fundamental reagent in research laboratories for exploring new synthetic methodologies and developing novel compounds.

Basic Information

Product Name	2-tert-Butoxycarbonylamino-Propionic Acid
CAS No.	9078-44-8
Molecular Formula	C8H15NO4
Molecular Weight	189.21 g/mol
Synonyms	Boc-Ala-OH; N-Boc-Alanine; N-(tert-Butoxycarbonyl)alanine; 2-[(tert-Butoxycarbonyl)amino]propanoic acid; Alanine, N-[(1,1-dimethylethoxy)carbonyl]-; (2S)-2-[(tert-Butoxycarbonyl)amino]propanoic acid (for L-isomer); BOC-L-ALANINE; N-tert-Butoxycarbonylalanine
EINECS	Contact for details

Quality Control

Our 2-tert-Butoxycarbonylamino-Propionic Acid is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC purity, chiral purity (where applicable), and identification by spectroscopic methods. A Certificate of Analysis (COA) detailing all relevant specifications is available for every batch upon request, supporting compliance in cGMP and research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	Contact for details
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.