Description

(E)-2-[2-Fluoro-2-(Quinuclidin-3-Ylidene)Ethoxy]-9H-Carbazole Monohydrochloride is a high-purity, advanced pharmaceutical intermediate with a distinct molecular architecture. This compound is critical for research and development in medicinal chemistry, particularly for its potential role in modulating specific biological targets. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of novel therapeutic agents. The product is supplied with a Certificate of Analysis to ensure batch-to-batch consistency and reliability for sensitive applications.

Application

• Pharmaceutical Intermediate: Key building block in the research and synthesis of new drug candidates, particularly in central nervous system (CNS) and oncology research.
• Medicinal Chemistry Research: Used as a core scaffold or precursor for structure-activity relationship (SAR) studies to optimize biological activity and selectivity.
• Biochemical Tool Compound: Serves as a reference standard or probe in pharmacological assays to study receptor interactions and enzyme inhibition.
• Process Development: Employed in scaling up synthetic routes for potential Active Pharmaceutical Ingredients (APIs) under Good Manufacturing Practice (GMP) guidelines.
• Academic Research: Utilized in university and institutional labs for fundamental studies in organic synthesis and heterocyclic chemistry.
• Contract Research Organizations (CROs): Supplied to CROs supporting drug discovery programs for client pharmaceutical companies.

Basic Information

Product Name	(E)-2-[2-Fluoro-2-(Quinuclidin-3-Ylidene)Ethoxy]-9H-Carbazole Monohydrochloride
CAS No.	9077-14-9
Molecular Formula	C21H20FN2O•HCl
Molecular Weight	380.86 g/mol
Synonyms	9H-Carbazole, 2-[2-fluoro-2-(quinuclidin-3-ylidene)ethoxy]-, monohydrochloride, (E)-; (E)-2-(2-Fluoro-2-(quinuclidin-3-ylidene)ethoxy)-9H-carbazole hydrochloride; Carbazole-quinuclidine derivative hydrochloride; 3-[(E)-2-(2-Carbazolyloxy)-1-fluoroethenyl]quinuclidine hydrochloride
EINECS	Contact for details

Quality Control

Every batch of (E)-2-[2-Fluoro-2-(Quinuclidin-3-Ylidene)Ethoxy]-9H-Carbazole Monohydrochloride is manufactured and controlled under a strict quality management system. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with research-grade and potential GMP-starting material standards. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your regulatory and R&D documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture uptake. For long-term storage, consider conditions under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥97.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Total impurities ≤3.0%; Any single impurity ≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.