Description

Hydroxyethyl Starch is a semi-synthetic, water-soluble polymer derived from waxy maize or potato starch, widely used as a plasma volume expander and rheology modifier. Its modified structure provides superior colloidal properties and stability compared to native starch, making it a critical functional ingredient. This product is essential for manufacturers in the pharmaceutical, biomedical, and specialty chemical industries seeking reliable, high-quality excipients and additives.

Application

• Pharmaceutical Formulations: Primarily used as a safe and effective plasma volume expander in intravenous infusion solutions for hypovolemia treatment.
• Biomedical Research: Serves as a cryoprotectant for cell and tissue preservation and as a component in cell culture media and diagnostic reagents.
• Controlled Drug Delivery: Acts as a biodegradable carrier or matrix in the development of sustained-release and targeted drug delivery systems.
• Cosmetics & Personal Care: Functions as a film-forming agent, texture enhancer, and stabilizer in creams, lotions, and hair care products.
• Industrial Applications: Employed as a thickener, binder, and sizing agent in paper coatings, textile processing, and adhesive formulations.
• Laboratory Reagent: Used in biochemical and molecular biology laboratories for gradient centrifugation and as a standard in viscosity measurements.

Basic Information

Product Name	Hydroxyethyl Starch
CAS No.	9005-27-0
Molecular Formula	(C6H10O5)n with hydroxyethyl substitution
Molecular Weight	Variable (Polymer)
Synonyms	HES; Hetastarch; Hydroxyethyl Starch; Hydroxyethyl ether of starch; Starch, 2-hydroxyethyl ether; Hydroxyethylated starch; HES 130/0.4; HES 200/0.5; HES 450/0.7; Plasma Volume Expander; α-Amylase treated hydroxyethyl starch
EINECS	232-686-1

Quality Control

Our Hydroxyethyl Starch is manufactured under strict quality management systems. Production adheres to current Good Manufacturing Practices (cGMP) and relevant pharmacopoeial standards, including USP-NF and Ph. Eur. monographs where applicable. Each batch undergoes comprehensive analytical testing for parameters such as molecular weight distribution, degree of substitution, purity, and microbiological quality. A detailed Certificate of Analysis (COA) is provided with every shipment to ensure full traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); the container must be kept tightly sealed after opening to prevent absorption of atmospheric moisture, which can affect product performance.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms
pH (10% solution)	5.0 - 7.5
Degree of Substitution	0.4 - 0.7 (Grade dependent)
Molecular Weight (Mw)	Specified per grade (e.g., 130 kDa, 200 kDa)
Assay (on dried basis)	≥ 95.0%
Loss on Drying	≤ 10.0%
Residue on Ignition	≤ 1.0%
Heavy Metals	≤ 20 ppm
Microbial Limits	Meets Ph. Eur./USP criteria
Endotoxin (for injectable grades)	< 0.5 EU/mg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.