Description

Nifuroxazide CAS NO 965-52-6 is a synthetic nitrofuran derivative with potent antibacterial and antiprotozoal activity. This compound is valued for its specific action against a range of enteric pathogens, making it a critical active pharmaceutical ingredient (API). It is primarily required by pharmaceutical manufacturers for the formulation of anti-diarrheal and gastrointestinal infection treatments.

Application

• Pharmaceutical API: Primary use as the active ingredient in oral anti-diarrheal medications.
• Gastrointestinal Infection Treatment: Formulated into tablets, capsules, and suspensions for bacterial and protozoal enteritis.
• Veterinary Medicine: Used in formulations to treat enteric infections in livestock and companion animals.
• Research & Development: Serves as a reference standard and a key intermediate in pharmacological and microbiological research.
• Chemical Synthesis: Acts as a precursor or intermediate in the synthesis of other nitrofuran-based pharmaceutical compounds.

Basic Information

Product Name	Nifuroxazide
CAS No.	965-52-6
Molecular Formula	C12H9N3O5
Molecular Weight	275.22 g/mol
Synonyms	4-Hydroxy-N'-[(5-nitro-2-furyl)methylene]benzohydrazide; Nifuroxazide; 5-Nitro-2-furaldehyde 4-hydroxybenzoylhydrazone; Ambilhar; Ercefuryl; Nifurazid; Nifurzide; Preparations containing nifuroxazide (e.g., Ercefuryl, Nifuroxazide-Ratiopharm)
EINECS	213-525-8

Quality Control

Our Nifuroxazide is manufactured under strict quality management systems. Each batch is tested to ensure compliance with relevant pharmacopoeial standards (e.g., in-house specifications aligned with EP/BP principles) for identity, purity, and potency. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and regulatory support.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials.

Specification

Item	Specification
Appearance	Yellow to orange-yellow crystalline powder
Identification (IR)	Conforms to standard
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any individual impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.