Description

6-Bromo-3-Pyridin-2-Yl-Chromen-2-One is a high-purity, synthetically valuable heterocyclic compound that serves as a critical building block in advanced organic synthesis. Its unique molecular architecture, featuring a fused chromen-2-one (coumarin) core substituted with bromine and a pyridinyl group, makes it an indispensable intermediate for pharmaceutical research and fine chemical manufacturing. This compound is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecular targets.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting kinase inhibition and other biological pathways.
• Agrochemical Research: Used in the development of new active ingredients for crop protection products.
• Material Science: Serves as a building block for organic electronic materials, such as OLED (Organic Light-Emitting Diode) emitters or charge transport materials.
• Chemical Biology: Employed as a fluorescent probe or tag due to the inherent photophysical properties of the coumarin scaffold.
• Academic & Contract Research: Utilized in universities and CROs (Contract Research Organizations) for methodological studies and the discovery of new chemical entities.
• Fine Chemical Synthesis: Acts as a versatile intermediate for further functionalization via cross-coupling reactions (e.g., Suzuki, Sonogashira) facilitated by the bromine substituent.

Basic Information

Product Name	6-Bromo-3-Pyridin-2-Yl-Chromen-2-One
CAS No.	958-58-7
Molecular Formula	C14H8BrNO2
Molecular Weight	302.13 g/mol
Synonyms	6-Bromo-3-(pyridin-2-yl)-2H-chromen-2-one; 6-Bromo-3-(2-pyridinyl)-2H-1-benzopyran-2-one; 3-(2-Pyridinyl)-6-bromo-2H-1-benzopyran-2-one; 6-Bromo-3-(2-pyridyl)coumarin; 2H-1-Benzopyran-2-one, 6-bromo-3-(2-pyridinyl)-; 958-58-7; 6-Bromo-3-pyridin-2-yl-chromen-2-one
EINECS	Contact for details

Quality Control

Our 6-Bromo-3-Pyridin-2-Yl-Chromen-2-One is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment. We can support development projects with custom purity grades and analytical data packages upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided. Keep container tightly sealed when not in use to protect from moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥97.0% (Area %)
Melting Point	Contact for details
Loss on Drying	≤0.5%
Heavy Metals	≤20 ppm
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.