Description

trans-4-tert-Butylcyclohexanecarboxylic Acid is a high-purity, sterically hindered alicyclic carboxylic acid characterized by its stable trans-conformation. This compound is a crucial chiral building block and intermediate in advanced organic synthesis, valued for its ability to impart conformational rigidity and influence stereochemistry. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing active ingredients and performance materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, particularly in creating molecules with defined stereocenters.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides where the tert-butylcyclohexyl moiety enhances biological activity and stability.
• Liquid Crystal Materials: Serves as a precursor in the manufacture of liquid crystal compounds for display technologies.
• Perfumery and Fragrance Ingredient: Acts as a starting material for synthesizing musky and woody aroma chemicals.
• Polymer Modification: Employed to introduce bulky side chains into polymers, modifying physical properties like glass transition temperature and solubility.
• Asymmetric Catalyst Ligand Precursor: Used to develop chiral ligands for metal-catalyzed asymmetric reactions.

Basic Information

Product Name	trans-4-tert-Butylcyclohexanecarboxylic Acid
CAS No.	943-29-3
Molecular Formula	C11H20O2
Molecular Weight	184.28 g/mol
Synonyms	trans-4-(tert-Butyl)cyclohexanecarboxylic Acid; 4-tert-Butylcyclohexanecarboxylic Acid (trans); (1r,4r)-4-(tert-Butyl)cyclohexane-1-carboxylic Acid; p-tert-Butylcyclohexanecarboxylic Acid (trans); NSC 3349; Cyclohexanecarboxylic acid, 4-(1,1-dimethylethyl)-, trans-; trans-4-tert-Butyl-1-cyclohexanecarboxylic Acid
EINECS	213-401-8

Quality Control

Our trans-4-tert-Butylcyclohexanecarboxylic Acid is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets exacting standards for research and industrial use. A Certificate of Analysis (COA) detailing identity, purity, and specific impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and heat sources.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% trans-isomer
Melting Point	118 - 122 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.